Patents Assigned to Rheinische Friedrich-Wilhelms-Universitat
  • Publication number: 20100048594
    Abstract: The invention relates to compounds selected from among the group comprising general formulas (1), (2), (3), and/or (4) and/or the enantiomers, diastereomers, and derivatives thereof, and the pharmaceutically acceptable salts thereof for producing a medicament used for therapeutically and/or preventively treating disease and pathological conditions linked to regulation of the insulin and/or insulin-like growth factor (IGF) signalling pathway and/or for chemically inducing longevity.
    Type: Application
    Filed: November 14, 2007
    Publication date: February 25, 2010
    Applicant: RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITAT
    Inventors: Michael Famulok, Markus Hafner, Anton Schmitz, Bernhard Fuss, Ingo Zinke, Michael Hoch
  • Publication number: 20090105286
    Abstract: The invention relates to drugs and the use thereof, wherein said drugs contain compounds selected from a group comprising general formulas (1), (2), (3) and (4) and/or enantiomers, diastereomers or the pharmaceutically acceptable salts thereof. Said drugs are used for treating autoimmune and tumoral diseases and/or for immunosuppresion.
    Type: Application
    Filed: November 18, 2005
    Publication date: April 23, 2009
    Applicant: Rheinische Friedrich-Wilhelms Universitat
    Inventors: Michael Famulok, Waldemar Kolanus, Markus Hafner, Imke Grune, Barbara Tappertzhofen, Mirko Theis
  • Publication number: 20090005338
    Abstract: A medicament containing a compound of the following formulas (Ia) and (Ib): wherein Z is selected from the group consisting of a covalent bond, at least one at least divalent hetero atom, a saturated, unsaturated, branched, unbranched and/or cyclic, substituted or unsubstituted hydrocarbon chain, a saturated or unsaturated, branched, unbranched and/or cyclic, substituted or unsubstituted hydrocarbon chain provided with hetero atoms in the chain thereof, or combinations thereof; R?1 to R?4 and R?1 to R?5 independently represent H, at least one hetero atom, especially oxygen, nitrogen or halogens, a saturated, unsaturated, branched, unbranched and/or cyclic, substituted or unsubstituted hydrocarbon chain, a saturated or unsaturated, branched, unbranched and/or cyclic, substituted or unsubstituted hydrocarbon chain provided with hetero atoms in the chain thereof, or combinations thereof; the two cyclopentadienyl rings are optionally linked together via any of residues R?1 to R?5; R1 and R2 independently r
    Type: Application
    Filed: November 19, 2007
    Publication date: January 1, 2009
    Applicants: Charite - Universitatsmedizin Berlin, Rheinische Friedrich-Wilhelms-Universitat Bonn
    Inventors: Andreas Gansauer, Aram Prokop, Anja Selig, Dieter Franke
  • Publication number: 20070264713
    Abstract: The invention relates to a process for cultivating undifferentiated stem cells in suspension and in particular to a method for cultivating stem cells on microcarriers in vessels. The method enables stem cells to be cultivated in a scalable process for the first time, without losing their pluripotentiality. Different types of vessels are suitable for cultivation, such as e.g. spinners and bioreactors. The option of precisely setting the cultivation conditions in said vessels aids the process of obtaining a pluripotentiality of the stem cells. the inventive method also permits large yields of stem cells of an unvarying quality to be produced.
    Type: Application
    Filed: September 9, 2005
    Publication date: November 15, 2007
    Applicant: RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSIT√ĄT
    Inventors: Stefanie Terstegge, Oliver Brustle