Patents Assigned to RHIZEN PHARMACEUTICALS AG
  • Kinase modulators
    Patent number: 11858907
    Abstract: The present invention provides PI3K protein kinase modulators of Formula (I) wherein R, n, R1, R2, L1, Cy1 and Cy2 are as defined herein, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: January 2, 2024
    Assignee: RHIZEN PHARMACEUTICALS AG
    Inventors: Meyyappan Muthuppalaniappan, Srikant Viswanadha, Govindarajulu Babu, Swaroop K. Vakkalanka
  • Process for preparation of optically pure and optionally substituted 2-(1-hydroxy-alkyl)-chromen-4-one derivatives and their use in preparing pharmaceuticals
    Patent number: 11478481
    Abstract: The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the processes, and to the use of the intermediates in the preparation of pharmaceuticals. In particular, the present invention concerns enantiomerically pure optionally substituted 2-(1-hydroxy-alkyl)-chromen-4-one derivatives represented by formula (IA) and (IB), processes for preparing the alcohol derivatives and their use in preparing pharmaceuticals.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: October 25, 2022
    Assignee: RHIZEN PHARMACEUTICALS AG
    Inventors: Jayaraman V. Raman, Swaroop K. Vakkalanka
  • Dual selective PI3 delta and gamma kinase inhibitors
    Patent number: 11466006
    Abstract: The present invention relates to dual delta (?) and gamma (?) PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of Pi3K kinase mediated diseases or disorders with them.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: October 11, 2022
    Assignee: RHIZEN PHARMACEUTICALS AG
    Inventors: Swaroop K. Vakkalanka, Prashant K. Bhavar, Srikant Viswanadha, Govindarajulu Babu
  • PI3K protein kinase inhibitors
    Patent number: 11352359
    Abstract: The present disclosure provides novel compounds useful as PI3K protein kinase modulators, in particular as PI3K delta (?) and/or gamma (?) protein kinase modulators. The present disclosure also provides methods for preparing PI3K protein kinase modulators, pharmaceutical compositions containing them, and methods of treatment, prevention and/or amelioration of PI3K kinase mediated diseases or disorders with them.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: June 7, 2022
    Assignee: RHIZEN PHARMACEUTICALS AG
    Inventors: Prashant Kashinath Bhavar, Swaroop Kumar Venkata Satya Vakkalanka, Govindarajulu Babu