Abstract: Novel polypeptides involved in the biosynthesis of cobalamines and/or cobamides, in particular coenzyme B12, genetic material responsible for expressing these polypeptides, and a method for preparing them, are described. A method for amplifying the production of cobalamines, and particularly coenzyme B12, using recombinant DNA techniques, are also described.
Type:
Grant
Filed:
April 21, 1995
Date of Patent:
December 2, 2003
Assignee:
Rhone-Poulenc Biochimie, et al.
Inventors:
Francis Blanche, Beatrice Cameron, Joel Crouzet, Laurent Debussche, Sophie Levy Schil, Denis Thibaut