Abstract: The present invention relates to quinazolinones and related compounds which are inhibitors of PARP14 and are useful, for example, in the treatment of cancer and inflammatory diseases.
Type:
Grant
Filed:
April 14, 2021
Date of Patent:
April 16, 2024
Assignee:
Ribon Therapeutics, Inc.
Inventors:
Laurie B. Schenkel, Melissa Marie Vasbinder, Kevin Wayne Kuntz, Kerren Kalai Swinger
Abstract: The present invention relates to pyridazinones and related compounds having Formula I: and pharmaceutically acceptable salts thereof, which are inhibitors of PARP7 and are useful in the treatment of cancer.
Type:
Grant
Filed:
October 29, 2020
Date of Patent:
July 4, 2023
Assignee:
Ribon Therapeutics, Inc.
Inventors:
Nicholas Robert Perl, Melissa Marie Vasbinder, Kevin Wayne Kuntz
Abstract: The present invention relates to pyridazinones and related compounds which are inhibitors of PARP7 and are useful in the treatment of cancer.
Type:
Grant
Filed:
April 12, 2021
Date of Patent:
January 31, 2023
Assignee:
Ribon Therapeutics, Inc.
Inventors:
Melissa Marie Vasbinder, Laurie B. Schenkel, Kerren Kalai Swinger, Kevin Wayne Kuntz
Abstract: The present invention relates to heterobicyclic amides and related compounds which are inhibitors of CD38 and are useful in the treatment of cancer.
Type:
Grant
Filed:
July 30, 2020
Date of Patent:
December 27, 2022
Assignee:
Ribon Therapeutics, Inc.
Inventors:
Laurie B. Schenkel, Melissa Marie Vasbinder, Kevin Wayne Kuntz, Nicholas Robert Perl, Jennifer Downing
Abstract: The present disclosure is related to methods of identifying Poly(ADP-ribose) polymerases (PARP) inhibitors, and the methods of using PARP probes.
Type:
Grant
Filed:
April 29, 2019
Date of Patent:
April 5, 2022
Assignee:
Ribon Therapeutics, Inc.
Inventors:
Timothy J. N. Wigle, Danielle J. Blackwell, Kevin Wayne Kuntz, Melissa Marie Vasbinder, Laurie B. Schenkel, Kerren Kalai Swinger
Abstract: The present invention relates to pyridazinones and related compounds which are inhibitors of PARP7 and are useful in the treatment of cancer.
Type:
Grant
Filed:
August 11, 2020
Date of Patent:
May 25, 2021
Assignee:
Ribon Therapeutics, Inc.
Inventors:
Melissa Marie Vasbinder, Laurie B. Schenkel, Kerren Kalai Swinger, Kevin Wayne Kuntz
Abstract: The present invention relates to quinazolinones and related compounds which are inhibitors of PARP14 and are useful, for example, in the treatment of cancer and inflammatory diseases.
Type:
Grant
Filed:
January 6, 2020
Date of Patent:
May 18, 2021
Assignee:
Ribon Therapeutics Inc.
Inventors:
Laurie B. Schenkel, Melissa Marie Vasbinder, Kevin Wayne Kuntz, Kerren Kalai Swinger
Abstract: The present invention relates to pyridazinones and related compounds which are inhibitors of PARP7 and are useful in the treatment of cancer.
Type:
Grant
Filed:
October 24, 2019
Date of Patent:
December 22, 2020
Assignee:
Ribon Therapeutics, Inc.
Inventors:
Melissa Marie Vasbinder, Laurie B. Schenkel, Kerren Kalai Swinger, Kevin Wayne Kuntz
Abstract: The present invention relates to quinazolinones and related compounds which are inhibitors of PARP14 and are useful, for example, in the treatment of cancer and inflammatory diseases.
Type:
Grant
Filed:
December 20, 2018
Date of Patent:
February 18, 2020
Assignee:
Ribon Therapeutics Inc.
Inventors:
Laurie B. Schenkel, Melissa Marie Vasbinder, Kevin Wayne Kuntz, Kerren Kalai Swinger
Abstract: The present invention relates to pyridazinones and related compounds which are inhibitors of PARP7 and are useful in the treatment of cancer.
Type:
Grant
Filed:
April 29, 2019
Date of Patent:
February 4, 2020
Assignee:
Ribon Therapeutics Inc.
Inventors:
Melissa Marie Vasbinder, Laurie B. Schenkel, Kerren Kalai Swinger, Kevin Wayne Kuntz