Patents Assigned to Ribopharma
  • Double-stranded RNA (dsRNA) and method of use for inhibiting expression of a fusion gene
    Publication number: 20030190654
    Abstract: The present invention relates to the specific inhibition of expression of a fusion gene in mammals using a short double stranded RNA. The dsRNA is approximately 19-24 nucleotides in length, and has a nucleotide sequence which is complementary to at least a part of the target gene. The dsRNAs of the present invention are useful for treating diseases caused by chromosomal aberrations, particularly malignant diseases such as lymphoma and leukemia.
    Type: Application
    Filed: January 22, 2003
    Publication date: October 9, 2003
    Applicant: Ribopharma
    Inventors: Olaf Heidenreich, Hans-Peter Vornlocher, Roland Kreutzer, Stefan Limmer