Patents Assigned to RiboTargets Holdings PLC
  • RNA oligonucleotides that bind HIV tat protein
    Patent number: 5821046
    Abstract: A synthetic molecule comprising an RNA binding sequence or sequences corresponding to the site bound by the HIV protein tat and capable of binding to tat within cells. The binding sequence or sequences, by binding tat within cells, can act to cause inhibition of growth of any HIV present in the cells, and so has potential therapeutic use in treatment of patients affected with HIV. The invention also provides an assay for identifying compounds that inhibit tat binding.
    Type: Grant
    Filed: October 10, 1995
    Date of Patent: October 13, 1998
    Assignee: RiboTargets Holdings PLC
    Inventors: Jonathan Karn, Michael John Gait, Shaun Heaphy, Colin Dingwall