Patents Assigned to Ribozyme Pharmaceutical, Inc.
  • Hairpin ribozymes
    Patent number: 6022962
    Abstract: Hairpin ribozyme lacking a substrate moiety, comprising atleast six bases in helix 2 and able to base-pair with a separate substrate RNA, wherein the said ribozyme comprises one or more bases 3' of helix 3 able to base-pair with the said substrate RNA to form a helix 5 and wherein the said ribozyme can cleave and/or ligate said separate RNA(s) in trans.
    Type: Grant
    Filed: June 16, 1998
    Date of Patent: February 8, 2000
    Assignee: Ribozyme Pharmaceutical, Inc.
    Inventors: Bharat Chowrira, James A. McSwiggen
  • Hairpin ribozymes
    Patent number: 5837855
    Abstract: Hairpin ribozyme lacking a substrate moiety, comprising at least six bases in helix 2 and able to base-pair with a separate substrate RNA, wherein the said ribozyme comprises one or more bases 3' of helix 3 able to base-pair with the said substrate RNA to form a helix 5 and wherein the said ribozyme can cleave and/or ligate said separate RNA(s) in trans.
    Type: Grant
    Filed: December 23, 1996
    Date of Patent: November 17, 1998
    Assignee: Ribozyme Pharmaceutical, Inc.
    Inventors: Bharat Chowrira, James McSwiggen