Abstract: A adjustable clamping device for applying pressure to a puncture site of an artery. The clamping device has a radial arm movably supported on a column which extends from a base. A carrier movably mounted on the end of the arm supports a pressure pad. The radial arm extends in a parallel attitude over the base and may be adjusted vertically upwardly and downwardly in reference to the base and may also be pivoted in reference to the column. Lateral movement of the arm facilitates positioning the pressure pad over the puncture site. A releasable feed mechanism on the arm controls movement of the carrier and thus the pressure pad. With the feed mechanism engaged, rotation of the carrier provides a controlled feeding of the carrier relative to the arm. With the feed mechanism disengaged, the carrier may be rapidly advanced or retracted. Independent locking mechanisms are provided for clamping of the lateral movement of the arm separate from the vertical and pivotal movements.