Abstract: Methods for stabilizing laser-induced graphene (LIG) through composite formation and compositions thereof. Using infiltration methods and/or lamination methods, LIG composites (LIGCs) with physical properties can be engineered on various substrate materials. The physical properties include surface properties, such as superhydrophobicity and antibiofouling; the LIGCs are also useful in antibacterial applications, Joule-heating applications, and as resistive memory device substrates. Further, methods for fabricating and using LIG for flexible and embeddable gas sensors.

Abstract: In some embodiments, devices for use as blood-brain barrier models are disclosed. The devices may include either a hydrogel component that surrounds a channel formed between a first opening and a second opening of the hydrogel component, or a hydrogel component that forms a groove. The devices may further include pericytes disposed in the channel or the groove, and endothelial cells may be disposed in the channel or the groove. The hydrogel component may include astrocytes (e.g., printed into the hydrogel component via projection stereolithography). Also disclosed are various methods of making and using these devices.

Abstract: Cytokine-bisphosphonate conjugates and methods of use thereof in muscle functions.

Abstract: Provided is a composite material including an electrically insulating upper layer; a conductive layer which promotes Joule heating; and a thermally insulating backing layer configured to provide support and thermal insulation. The conductive layer is adhered to the thermally insulating backing layer, and the electrically insulating upper layer is adhered to the conductive layer. Also provided are an article including the composite material; a method of fabricating the composite material; a system including the composite material, a controller, and a power source; a method of thermally decontaminating the composite material; and method of thermoregulation.

Abstract: Methods for the synthesis of graphene, and more particularly the method of synthesizing graphene by flash Joule heating (FJH). Such methods can be used to synthesize turbostratic graphene (including low-defect turbostratic graphene) in bulk quantities. Such methods can further be used to synthesize composite materials and 2D materials.

Abstract: A wearable haptic device and system for providing spatiotemporal cues are disclosed. The system includes a wearable haptic device and a controller. The wearable haptic device includes a fluidic circuit having, at least one fluidic capacitor, wherein each of the at least one fluidic capacitor comprises an inflatable cell formed from a portion of a first material sheet bonded to a portion of a second material sheet to form a hermetic bond, at least one channel fluidically connected to the fluidic capacitor, each of the at least one channel is configured to convey a pressurized fluid to the at least one fluidic capacitor, a master valve, fluidically connected to the at least one channel, and a fluid source fluidically connected to the at least one fluidic capacitor via the at least one channel. The controller sends and receives signals to deliver pressurized fluid to the at least one fluidic capacitor.

Abstract: The present disclosure is directed to designed fusion proteins derived from MTFs with strong potency to modulate transcription and designated these recombinant fusion proteins MSN and NMS. These powerful transactivators potently activate transcription from endogenous loci when recruited through CRISPR-dCas9, Zinc Finger, or TALE system proteins. This technology permits upregulation of gene expression in targeted manner devoid of viral transcription activation domains and is amenable to high-throughput screening. These synthetic transcription activators interact with all programable DNA binding proteins tested and have exhibited applicability in vitro for efficient lineage conversion.

Abstract: A method of forming a perovskite film includes depositing an ink onto a substrate and annealing the substrate to form the perovskite film. The ink includes one or more 2D perovskite crystals; one or more group one cations or ammonium halides; one or more metal halides; and one or more solvents. A perovskite ink includes one or more 2D perovskite crystals, one or more group one cations or ammonium halides, one or more metal halides and one or more solvents.

Abstract: Nanocomposites include boron nitride doped with a metal, where the boron nitride doped with a metal is catalytically active for degrading a perfluoroalkyl substance. Methods of making nanocomposites include forming a mixture by adding a salt comprising a metal cation to a powder comprising boron nitride; forming a dispersion by adding the mixture to a eutectic solvent; and reacting the metal with the boron nitride to form a product comprising the nanocomposite by heating the dispersion. Methods of treating a perfluoroalkyl substance include contacting the perfluoroalkyl substance with a nanocomposite comprising boron nitride doped with a metal; and degrading the perfluoroalkyl substance with the nanocomposite.

Abstract: Embodiments of the present disclosure pertain to methods of making a carbon nanotube hybrid material by depositing a catalyst solution onto a carbon-based material, and growing carbon nanotubes on the carbon-based material such that the grown carbon nanotubes become covalently linked to the carbon-based material through carbon-carbon bonds. The catalyst solution includes a metal component (e.g., iron) and a buffer component (e.g., aluminum) that may be in the form of particles. The metal component of the particle may be in the form of a metallic core or metallic oxide core while the buffer component may be on a surface of the metal component in the form of metal or metal oxides. Further embodiments of the present disclosure pertain to the catalytic particles and carbon nanotube hybrid materials. The carbon nanotube hybrid materials of the present disclosure may be incorporated as electrodes (e.g., anodes or cathodes) in energy storage devices.

Abstract: Provided herein are compositions comprising multi domain peptide (MDP) hydrogels where the peptides that constitute the hydrogel have at least one N6-(1-iminoethyl)-lysine side chain. Also provided are hydrogels that further comprise a STING agonist, an immune checkpoint inhibitor, and/or an anti-cancer therapy. Also provided are methods of using such compositions in the treatment of cancer.

Abstract: The present disclosure provides methods for treating bone disease, such as bone cancers or bone metastasis of cancers, by administering an engineered bone-targeting compositions, such as an antibody or one or more polypeptides, such as an antibody or polypeptide engineered to comprise bone-homing peptide(s). Further provided herein are bone-targeting compositions, such as an antibody or one or more polypeptides, such as an antibody or polypeptide engineered to comprise bone-homing peptide(s).

Abstract: Some disclosed embodiments relate to a system (and/or use of or manufacturing) that includes: a magnetoelectric (ME) component comprising: one or more first layers, wherein each of the one or more first layers comprises a piezoelectric material; one or more second layers, wherein each of the one or more second layers comprises a magnetostrictive material, and wherein a thickness ratio that is defined to be a cumulative thickness of the one or more first layers relative to a cumulative thickness of the one or more second layers is between 0.2 and 0.5. The system may also include an energy harvesting circuit comprising a rectifier circuit, where the energy harvesting circuit is coupled to the ME component.

Abstract: Systems and methods for producing a covalent organic framework including providing a first monomer to a first zone in a furnace, a second monomer to a second zone in the furnace, and a substrate to a third zone in the furnace, where the third zone is located downstream from the first zone and the second zone. Systems and methods also include heating the furnace to a achieve temperature profile having a range of temperatures where the range of temperatures vaporizes the first monomer the second monomer. Systems and methods further include absorbing, onto the substrate, the first vaporized monomer and the second vaporized monomer to produce a covalent organic framework (COF). Articles produced by systems and methods include a film of a covalent organic framework (COF). The COF is a reaction product of a first monomer and a second monomer, and the COF is arranged in a two-dimensional crystalline lattice.

Abstract: This document relates to epoxy compositions containing a sliding-ring polymer (polyrotaxane) additive and a thermally-curable epoxy resin. The epoxy compositions exhibit increased flexural toughness and impact resistance as compared to the same epoxy composition that does not contain the additive. This document also relates to 3D-printed epoxy compositions containing a sliding-ring polymer (polyrotaxane) additive and a thermally-curable epoxy resin.

Abstract: An electrochemical cell with a lithium-metal anode that suppresses dendrite formation and can be fabricated using a simple, inexpensive, and solvent-free process. The anode is coated with a layer of disordered nanomaterial, saturated with lithium ions, that suppresses dendrite formation during charging. The dendrite-suppression coating can be applied simply using a dry, abrasive technique in which the lithium-metal anode is alternately abraded to roughen the surface and polished using a polishing powder of a material that alloys with the lithium.

Abstract: Gas sensors having laser-induced graphene (LIG) and/or LIG composites, and methods of making and using gas sensors having LIG and/or LIG composites.

Abstract: An microheater array system includes an integrated microheater array configured to generate a localized heat and having a plurality of pixels. Each pixel includes: an inductor; a stacked oscillator configured to generate a magnetic field at microwave frequencies with tunable intensity and frequency; and an electro-thermal loop. The microheater array system may further include a plurality of magnetic nanoparticles (MNPs).

Abstract: Exemplary methods, compositions and uses thereof can be provided for preventing, reducing and/or treating loss of muscle function. In particular, e.g., it is possible to administer to a subject a pharmaceutical composition comprising a therapeutically effective amount of an agent that enhances Interleukin-6 (IL) release during exercise, and optionally a pharmaceutically acceptable carrier or excipient.

Abstract: Embodiments disclosed herein generally relate to wirelessly monitoring and controlling implantable magnetoelectric devices. Particularly, aspects of the present disclosure are directed to a system that includes an implantable device, a base station, and one or more sensors that are physically connected or wirelessly connected to the base station. The implantable device includes a magnetoelectric film, an electrical circuit coupled to the magnetoelectric film, and one or more electrodes. The base station includes a magnetic field generator and a magnetic transceiver.