Patents Assigned to Rich Technologies Holding Company, LLC
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Patent number: 11497207Abstract: A device that can be used to store blood product and/or cellular culture that may or may not be under pressure. The device includes a chamber that can be hermetically sealed and a flexible secondary bag which can be placed in the chamber. The chamber is designed to receive at least one secondary bag that contains a conventional storage bag containing blood product and/or cellular culture. The storage conditions are created in the chamber and may or may not include 1) creating a pressure higher than atmospheric pressure, 2) creating a refrigerated temperature, and/or 3) providing agitation to the secondary bag. The secondary bag is filled with a gas system that is used to facilitate in the storage of the blood product and/or cellular culture. The secondary bag can be made of a material and/or include a coating or film that is impermeable to the gas system and to the gas inside the chamber.Type: GrantFiled: January 31, 2018Date of Patent: November 15, 2022Assignee: Rich Technologies Holding Company, LLCInventor: Ilya Ilyin
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Patent number: 11166451Abstract: A method for platelet preservation comprising placing a composition comprising platelets in a gas mixture comprising xenon and oxygen under pressure of about 0-10 Bars at a first temperature of about 18° C.-37° C. for a first period of time, and then subsequently cooling the composition to a second temperature of about 0,1° C.-6° C., and holding the composition under the pressure and in the second temperature for a second period of time.Type: GrantFiled: September 26, 2012Date of Patent: November 9, 2021Assignee: Rich Technologies Holding Company, LLCInventors: Ilya Ilyin, Semyon Kogan, William E. Grieshober, Jr., James S. Jones, Alexander N. Shumeev, Stanislav A. Kolchanov, Yana A. Filkina, Yuriy Punin, Natella I. Enukashvily
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Patent number: 10412957Abstract: A system, method, and device for preserving blood and its components is described. The system and method generally include a device having a body defining a chamber, the chamber being configured to receive at least one bag containing blood or its components, the at least one bag being permeable to gas, for example, xenon. A cover is hermetically sealable to the body. An inlet is in fluid communication with the chamber. A pressure indicator is configured to indicate pressure in the chamber, the pressure indicator including a conduit containing a liquid. A portion of the conduit is transparent such that the liquid is visible. A source of pressurized gas, such as xenon, is provided to provide the pressurized gas to the chamber.Type: GrantFiled: January 24, 2017Date of Patent: September 17, 2019Assignee: Rich Technologies Holding Company, LLCInventors: Ilya Ilyin, Semyon Kogan, William E. Grieshober, Jr., Igor Kachko, Vladimir Vasiliev, Stanislav Kolchanov, Yuriy Punin, Mark Bakhrakh, Alexander N. Schumeev
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Patent number: 10123528Abstract: A method for preserving erythrocytes comprising the steps of obtaining an erythrocyte concentrate; subjecting the erythrocyte concentrate to a gas system that includes 65% to 100% by volume and optionally one or more ballast gases from 0% to 35% by volume; and, maintaining the erythrocyte concentrate that has been subjected to the gas system at a temperature that is above the freezing point of the erythrocyte concentrate and up to a temperature of about 30° C.Type: GrantFiled: November 19, 2013Date of Patent: November 13, 2018Assignee: Rich Technologies Holding Company, LLCInventors: Ilya Ilyin, Larry J. Dumont
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Patent number: 10098340Abstract: Provided is a method for reducing apoptosis in nucleated cells. The method entails holding nucleated cells in a container and adding a gas containing xenon to the container so that the pressure inside the container reaches between 0.5 to 4.0 Atm above ambient pressure; holding the container at between 0.5 to 4.0 Atm above ambient pressure for a period of time during which the temperature in the container is between 22° C. and 37° C.; lowering the temperature in the container to between 0.1° C. and 10° C. while maintaining the pressure of 0.5 to 4.0 Atm above ambient pressure and holding the container for a period of time; and reducing the pressure in the container to ambient pressure and increasing the temperature to 22° C.-37° C. By performing these steps, the cells undergo less apoptosis than a reference.Type: GrantFiled: February 3, 2012Date of Patent: October 16, 2018Assignee: Rich Technologies Holding Company, LLCInventors: William E. Grieshober, Jr., James S. Jones, Semyon Kogan, Ilya Ilyin, Natella I. Enukashvily, Yana A. Filkina, Alexander N. Shumeev, Stanislav Kolchanov
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Patent number: 9743660Abstract: A system, method, and device for preserving blood and its components is described. The system and method generally include a device having a body defining a chamber, the chamber being configured to receive at least one bag containing blood or its components, the at least one bag being permeable to gas, for example, xenon. A cover is hermetically sealable to the body. An inlet is in fluid communication with the chamber. A pressure indicator is configured to indicate pressure in the chamber, the pressure indicator including a conduit containing a liquid. A portion of the conduit is transparent such that the liquid is visible. A source of pressurized gas, such as xenon, is provided to provide the pressurized gas to the chamber.Type: GrantFiled: June 21, 2012Date of Patent: August 29, 2017Assignee: Rich Technologies Holding Company, LLCInventors: Ilya Ilyin, Semyon Kogan, William E. Grieshober, Jr., Igor Kachko, Vladimir Vasiliev, Stanislav A. Kolchanov, Yuriy Punin, Mark Bakhrakh, Alexander N. Shumeev
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Patent number: 9686978Abstract: A method and a platelet concentrate preservation device for platelet concentrate storage. A method includes at least partially saturating platelet concentrate xenon, and storing the platelet concentrate at less than 15 C in a generally horizontal position. A device can be used to store blood, blood products, or combinations thereof that may or may not be under pressure. The device includes a chamber having a cavity. The chamber includes first and second chamber parts that form the cavity when releasably connected together. The cavity is designed to receive at least one bag that contains the blood, blood products, or combinations thereof. The device also includes a high-strength casing and includes a chamber cavity. The high-strength casing includes first and second casing parts that form the chamber cavity when releasably connected together. The chamber cavity is designed to receive the chamber.Type: GrantFiled: December 11, 2013Date of Patent: June 27, 2017Assignee: Rich Technologies Holding Company, LLCInventors: Ilya Ilyin, Igor Kachko, Alexander Shumeev, Yuri Punin, Stanislav Kolchanov