Patents Assigned to Richard-Allan Scientific Company
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Patent number: 9546937Abstract: A tissue cassette includes a body having a first floor and a first perimeter wall encircling and extending from the first floor so that the first floor and first perimeter wall at least partially bound a body cavity, the first floor having a plurality of spaced apart openings extending therethrough. A mold has a second floor and a second perimeter wall encircling and extending from the second floor so that the second floor and second perimeter wall at least partially bound a mold cavity, the second floor having at least one micropore extending therethrough, the at least one micropore having a maximum diameter less than 0.040 inches. A hinge couples the body to the mold so that the body and mold can move between a closed position wherein the first floor overlies the second floor so as to form a tissue compartment therebetween and an open position.Type: GrantFiled: January 24, 2013Date of Patent: January 17, 2017Assignees: Richard-Allan Scientific Company, Western Michigan University Research Foundation (WMURF)Inventors: Jennifer H. Freeland, Keith O. Whittlinger, Parviz Merati, Nathanael J. Cooper
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Patent number: 8753836Abstract: Dewaxing buffers containing a water-soluble organic solvent, methods for use thereof, and kits incorporating dewaxing buffers. The dewaxing buffers contain a water soluble organic solvent that has a boiling point of at least 80° C. The dewaxing buffers described herein can be used to quickly and efficiently remove embedding paraffin from slide-mounted tissue sections in an aqueous buffer solution at elevated temperature without fear of paraffin redeposition of the slides. In addition, the dewaxing buffers described herein can be used to perform dewaxing and HIER in a single step, which can substantially reduce protocol time and lower the risk of sample loss or damage.Type: GrantFiled: January 23, 2012Date of Patent: June 17, 2014Assignee: Richard-Allan Scientific CompanyInventors: Jennifer H. Freeland, Marsha A. Harvey
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Publication number: 20130196371Abstract: A tissue cassette includes a body having a first floor and a first perimeter wall encircling and extending from the first floor so that the first floor and first perimeter wall at least partially bound a body cavity, the first floor having a plurality of spaced apart openings extending therethrough. A mold has a second floor and a second perimeter wall encircling and extending from the second floor so that the second floor and second perimeter wall at least partially bound a mold cavity, the second floor having at least one micropore extending therethrough, the at least one micropore having a maximum diameter less than 0.040 inches. A hinge couples the body to the mold so that the body and mold can move between a closed position wherein the first floor overlies the second floor so as to form a tissue compartment therebetween and an open position.Type: ApplicationFiled: January 24, 2013Publication date: August 1, 2013Applicants: Western Michigan University Research Foundation (WMURF), Richard-Allan Scientific CompanyInventors: Richard-Allan Scientific Company, Western Michigan University Research Foundation (WMURF)
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Publication number: 20130189730Abstract: Dewaxing buffers containing a water-soluble organic solvent, methods for use thereof, and kits incorporating dewaxing buffers. The dewaxing buffers contain a water soluble organic solvent that has a boiling point of at least 80° C. The dewaxing buffers described herein can be used to quickly and efficiently remove embedding paraffin from slide-mounted tissue sections in an aqueous buffer solution at elevated temperature without fear of paraffin redeposition of the slides. In addition, the dewaxing buffers described herein can be used to perform dewaxing and HIER in a single step, which can substantially reduce protocol time and lower the risk of sample loss or damage.Type: ApplicationFiled: January 23, 2012Publication date: July 25, 2013Applicant: RICHARD-ALLAN SCIENTIFIC COMPANYInventors: Jennifer H. Freeland, Marsha A. Harvey
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Patent number: 8158381Abstract: Methods that combine processing and staining of tissue samples such that the processed tissue is stained and ready for histological evaluation prior to embedding and sectioning, and separate staining of the sectioned tissue is not required. The method may be used with chemical and/or mechanical/thermal tissue penetrant enhancers in an automated tissue processing system.Type: GrantFiled: February 11, 2009Date of Patent: April 17, 2012Assignee: Richard-Allan Scientific CompanyInventors: J. Gary Wiederhold, Nathan T. Brinn
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Patent number: 7666620Abstract: A method for processing a biological tissue specimen using either manual or automated processing. The tissue specimen is sequentially contacted with components of a reagent system in the presence of increased temperature and/or agitation and in the absence of exogenous microwave radiation to facilitate processing in less than one working day.Type: GrantFiled: November 8, 2006Date of Patent: February 23, 2010Assignee: Richard-Allan Scientific CompanyInventor: J. Gary Wiederhold
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Publication number: 20090246824Abstract: Methods that combine processing and staining of tissue samples such that the processed tissue is stained and ready for histological evaluation prior to embedding and sectioning, and separate staining of the sectioned tissue is not required. The method may be used with chemical and/or mechanical/thermal tissue penetrant enhancers in an automated tissue processing system.Type: ApplicationFiled: February 11, 2009Publication date: October 1, 2009Applicant: Richard-Allan Scientific CompanyInventors: J. Gary Wiederhold, Nathan T. Brinn
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Publication number: 20080108043Abstract: A method for processing a biological tissue specimen using either manual or automated processing. The tissue specimen is sequentially contacted with components of a reagent system in the presence of increased temperature and/or agitation and in the absence of exogenous microwave radiation to facilitate processing in less than one working day.Type: ApplicationFiled: November 8, 2006Publication date: May 8, 2008Applicant: RICHARD-ALLAN SCIENTIFIC COMPANYInventor: J. Gary Wiederhold