Abstract: We disclose that a target organ such as kidney can be regenerated by complementing a developmental deficiency leading to a lack of development of the target organ in a non-human first mammal by injecting a somatic cell nuclear transfer cell (SCNT cell) into a developed blastocyst of the non-human first mammal. We also disclose a method for producing a target organ, using an SCNT cell, in a living body of a non-human first mammal having an abnormality associated with a lack of development of the target organ in a development stage, the target organ produced being derived from a second mammal that is an individual different from the non-human first mammal.

Abstract: Methods, compositions, and medical device systems relating to treating exercise-induced pulmonary hemorrhage (EIPH) and nasopharyngeal cicatrix (NC) in a mammal. For example, one method comprises administering through inhalation a composition comprising a physiologically acceptable carrier and one or more stem cell derived factors, such as stem cell factors secreted by cultured mesenchymal stem cells (MSCs). The mammal may be a horse, dog, camel, or Homo sapiens.