Abstract: A method for quality control of species used in analytical or diagnostic or therapeutic procedures includes immobilization of a model of the malignancy to a solid support (121), contacting the solid support with species dissolved in liquid (122), measuring both the rate of formation of complex and absolute magnitude of number of complexes of model and species (123) and determining the quality of species by comparing the measured values with predetermined values.

Abstract: A method of analysis or diagnosis of solid objects is based on real-time detection of how predefined probes interact with structures present on or in the solid object combined with the calculation of how the recorded binding curves of said probes are distributed in terms of interaction properties. The interaction properties are input to a classification algorithm which automatically determines statues of the solid object. The method is particularly advantageous for solid biological objects like tissue slices combined with antibody probes, said antibody recognizing receptors known to be over-expressed in disease states on said tissue slice.

Abstract: A device detects interactions between species in liquid and species on a solid support. It includes a solid support (11), a mechanism (16) for temporarily reducing the amount of a liquid to which the support is exposed, a detector (12) capable of detecting an interaction between species attached to the solid support, and species contained in the liquid. Also described is a method including attaching a first species on a solid support, exposing the first species to a liquid containing a second species, performing a measurement, capable of detecting an interaction between the first and the second species, and a reference measurement. The liquid is temporarily removed during the measurement.