Abstract: An integrated drug selection system centered around point-of-care dispensing assembly that provides a practical, cost effective, and convenient way to optimize and individualize drug treatments. Through the cloud-based platform the dispensing assembly can be linked to the patient-user, prescriber-user, pharmacy-user, and the like, via network communication protocols and techniques. The dispensing assembly can include a drug reservoir assembly and a drug dispensing section (or base). The drug reservoir assembly is rotated between one or more rotatable drug reservoirs to dispense different drugs. The system includes a cloud-based platform that uses software to process and facilitate dispensing, treatments, data, monitoring, notifications, and trials, including treatment of specific health conditions.