Abstract: Strains of human-derived bacteria have been obtained from complex fecal samples and shown to induce accumulation of Th17 cells in the intestine and promote immune functions. Pharmaceutical compositions containing these bacteria can be used as anti-infectives and as adjuvants in mucosal vaccines.
May 14, 2021
Date of Patent:
November 28, 2023
RIKEN, The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
Kenya Honda, Koji Atarashi, Masahira Hattori, Hidetoshi Morita
Abstract: A control method of controlling a computer to analyze, at a second facility, nucleic acid sequence data obtained, at a first facility, by a sequencer that reads a nucleic acid sequence, for a gene panel test, comprising receiving, from the first facility via a network, a sequence data set comprising a plurality of nucleic acid sequence data obtained by the sequencer corresponding to each of a plurality of library samples comprising a first library sample and a second library sample, which are prepared from a specimen of a subject, and link information indicating that the first library sample and the second library sample are prepared from the specimen of the same subject; analyzing a first sequence data and a second sequence data corresponding to each of the first library sample and the second library sample linked by the link information; and outputting analysis information based on an analysis result of the first sequence data and an analysis result of the second sequence data, is disclosed.
Abstract: A neutron emission unit is configured to emit neutrons such that a center axis (Nh) of a neutron emission intersects a center axis direction of collimators (23a to 23e). A calculation unit is capable of generating information about an inspection object in the center axis direction of the collimators, based on position information of a neutron detector and/or position information of the neutron emission unit, information about an angle (?1) at which the center axis of the neutron emission intersects the center axis direction of the collimators, and a neutron amount detected by the neutron detector.
Abstract: A non-destructive inspection system 1 includes a neutron radiation source 3 capable of emitting neutrons N, and a neutron detector 14 capable of detecting neutrons Nb produced via an inspection object 6a among neutrons N emitted from the neutron radiation source 3. The neutron radiation source 3 includes a linear accelerator 11 capable of emitting charged particles P accelerated; a first magnet section 12 including magnets 12a and 12b facing each other, the magnets 12a and 12b being capable of deflecting the charged particles P in a direction substantially perpendicular to a direction of emission of the charged particles P from the linear accelerator 11; and a target section 13 capable of producing neutrons N by being irradiated with the charged particles P that have passed through the first magnet section 12.
Abstract: An ophthalmic information processing apparatus includes a determiner and a detector. The determiner is configured to determine a presence or absence of a disc hemorrhage for a front image of a fundus of a subject's eye, using a disc hemorrhage determination model obtained by performing machine learning using a plurality of fundus images labeled with labels indicating the presence or absence of a disc hemorrhage as first teaching data. The detector is configured to detect a disc hemorrhage region depicted in the front image that is determined to have the disc hemorrhage, using a disc hemorrhage region detection model obtained by performing machine learning using a plurality of pairs of image groups as second teaching data, each pair having a front image of a fundus and a disc hemorrhage region image representing a disc hemorrhage region depicted in the front image.
Abstract: An ophthalmic information processing apparatus includes an acquisition unit and a disease estimation unit. The acquisition unit is configured to acquire a plurality of images with different cross-sectional orientations from each other of a subject’s eye. The disease estimation unit is configured to output estimation information for estimating whether or not the subject’s eye is a glaucoma eye from the images, using a plurality of learned models obtained by performing machine learning for each type of the images.
Abstract: A medical system according to an aspect example includes a data acquiring unit and a data processor. The data acquiring unit is configured to acquire from a patient two or more types of data among blood oxygen saturation data, auscultatory sound data, ocular image data, and ocular blood flow data. The data processor is configured to process the two or more types of data acquired by the data acquiring unit to detect a conditional change in a circulatory system associated with an infectious disease.
Abstract: To provide a manganese-iridium composite oxide, a manganese-iridium composite oxide and a manganese-iridium composite oxide electrode material, having high catalytic activity produced at low cost, to be used as an anode catalyst for oxygen evolution in water electrolysis, and their production methods. A manganese-iridium composite oxide, which has an iridium metal content ratio (iridium/(manganese+indium)) of 0.1 atomic % or more and 30 atomic % or less, and has interplanar spacings of at least 0.243±0.002 nm, 0.214±0.002 nm, 0.165±0.002 nm, 0.140±0.002 nm, and a manganese-iridium composite oxide electrode material comprising an electrically conductive substrate constituted by fibers at least part of which are covered with the above manganese-iridium composite oxide.
Abstract: According to a medical system of an aspect example, an ophthalmic data acquiring unit includes at least one ophthalmic examination apparatus for acquiring ophthalmic data from a patient, and an internal medicine data acquiring unit includes at least one internal medicine examination apparatus for acquiring internal medicine data from the patient. An inference processor is configured to perform inference processing using a trained model constructed by machine learning using training data that includes ophthalmic data, internal medicine data, and diagnostic result data. The inference processor generates inferred diagnostic data by performing the inference processing based at least on the ophthalmic data of the patient acquired by the ophthalmic data acquiring unit and the internal medicine data of the patient acquired by the internal medicine data acquiring unit. An output unit outputs a result of the inference processing performed by the inference processor.
Abstract: The toy flute is configured such that: a reciprocating body is accommodated inside a cylindrical body in a reciprocating manner; the cylindrical body is installed at an inner side of an opening section provided at a hollow body in such a manner that a vent hole at one side from among two vent holes provided at the abovementioned cylindrical body can communicate with the abovementioned opening section; and a flute section is installed at the abovementioned cylindrical body in such a manner that airflow flowing between the abovementioned opening section and a vent hole at the other side from among the abovementioned two vent holes causes sound to occur and reverberate inside the cylindrical body.
Abstract: An iron-based sintered alloy having improved thermal and mechanical strength is provided. The iron-based sintered alloy with dispersed hard particles comprises: a matrix comprising, by weight, 0.4 to 2% silicon (Si), 2 to 12% nickel (Ni), 3 to 12% molybdenum (Mo), 0.5 to 5% chromium (Cr), 0.6 to 4% vanadium (V), 0.1 to 3% niobium (Nb), 0.5 to 2% carbon (C), and the reminder of iron (Fe); and hard particles comprising 60 to 70% molybdenum (Mo), 0.3 to 1% boron (B), 0.1% or less carbon (C), and the reminder of iron (Fe). The hard particles are dispersed in the matrix in an amount in the range of 3 to 20% based on the entire alloy. They are sintered to produce the iron-based sintered alloy. Addition of boron into the ferromolybdenum hard particles enhances the wettability of the ferromolybdenum hard particles to prevent the hard particles from falling off the matrix.
Abstract: A side rail is formed into a ring shape having its generally rectangular section that has an outer surface 3 formed with a pair of edge surfaces 5 of small radius, and an intermediate surface 6 of large radius of curvature formed between the edge surfaces 5. When the side rail is in the inclined condition in operation, each edge surface 5 can easily ride on oil film on cylinder 16 and allow the side rail 1 to perform smooth sliding movement on the inner surface of cylinder. The intermediate surface 6 efficiently scrapes lubricating oil on cylinder to form lubricating oil film of necessary and minimum thickness between an inner surface 17 of cylinder 16 and side rail 1. Also, the larger radius of curvature for forming the intermediate surface 6 provides a larger contact area to the inner surface 17 of cylinder 16 to improve wear resistance.
Abstract: A two piece oil control ring is provided which comprises a ring body (1) formed into a generally M- or I-shaped section with an annular groove (4) on an inside surface (3) of the ring body (1); and a coiled expander (2) attached in the annular groove (4) of the ring body (1) for resiliently urging the ring body (1) toward an inner wall of a cylinder. The ring body (1) is made of stainless steel that contains chromium of 3.0 to 13.0 weight % with the outer and inner circumferential surfaces (11, 12) covered with nitrided layers (14, 15). Circular ratio (&tgr;) of an outer edge length (Yo) to an inner edge length (Yi) in the cross section of the ring body (1) is in a range between 1.08 and 1.32 to keep precise peripheral circularity of the ring body so that the nitrided layers survive lapping of the ring body (14, 15).
Abstract: A scale formation-inhibitory agent used in a welding treatment comprises a polymer selected from the group consisting of polymers having oxygen atoms in the main chain and polymers capable of being thermally depolymerized. The scale formation-inhibitory agent can inhibit the formation of scale on the surface of a metal part to be welded during a welding treatment.
Abstract: The oil control ring 1 is provided to attach in an annular groove 10 formed in a piston 2 for internal combustion engine. The spacer expander 4 comprises a base 8, a plurality of supports 6 and a plurality of arms 7. The supports 6 and arms 7 are integrally formed with the base 8 to extend from an outer periphery 8a or inner periphery 8b of the base 8. The supports 6 resiliently urge a side rail 5 mounted on the space expander 4 toward an upper surface 14 of the annular groove 10 so that during upward stroke of the piston 2, the supports 6 can be resiliently deformed to form between the side rail 5 and upper surface 14 of the groove 10 a radial passage through which oil scraped by the side rail can be drained. Each arm 7 is provided with a lug 8 to resiliently urge the side rail 5 in radial and outward direction.
Abstract: In a shoe 5 for a swash plate compressor, the conical tapered surface 13 is formed between the spherical surface 10 and the rounded edge 14 to converge toward the spherical surface 10 inside an imaginary spherical surface 15 including the spherical surface 10. The conical tapered surface 13 forms a relatively large arcuate gap 23 between the hemispherical concavity 7 and the conical tapered surface 13. The arcuate gap 23 serves to reserve necessary amount of lubricant oil which may be supplied to sliding portions between the spherical surface 10 of the convex surface 11 and hemispherical concavity 7 of the piston 2. In addition, upon manufacture of the shoe 5, it can easily be removed from a metallic mold 52 due to existence of the arcuate gap 23 which prevents tight fit of the shoe 5 in the mold 52.
October 7, 1997
Date of Patent:
April 27, 1999
Takehiro Sugawara, Masayuki Nagase, Jun Yamazaki, Kou Yonesaka
Abstract: A method and a detector for detecting nitrogen oxide in test gas are provided wherein test gas which contains NOx and interference gases is supplied through an oxygen feeder 4 into a measuring chamber 1a, and the interference gases are oxidized by oxygen or oxygen ion supplied to the measuring chamber 1a through oxygen feeder 4. A total amount of NOx in the test gas is detected based on a level of EMF produced between a first electrode 2 for detecting oxygen and NO2 gas and a second electrode 3 for detecting oxygen.
Abstract: An iron base sintered alloy with dispersed hard particles is provided which comprises by weight 3 to 15% nickel (Ni), 0.5 to 5% chromium (Cr), 0.5 to 2.0% carbon (C), the remainder iron (Fe) and unavoidable impurities. At least a part of nickel (Ni), molybdenum (Mo) and chromium (Cr) is contained in solid solution of an iron base matrix. At least a part of molybdenum (Mo) and chromium (Cr) is dispersed within the iron base matrix to form fine carbides or intermetallic compounds thereof. Uniformly dispersed within the iron base matrix are hard particles of 3 to 20% contain 50 to 57% chromium (Cr), 18 to 22% molybdenum (Mo), 8 to 12% cobalt (Co), 0.1 to 1.4% carbon (C), 0.8 to 1.3% silicon (Si) and the remainder iron (Fe) to strengthen the dispersion and remarkably improve wear resistance.
January 22, 1997
Date of Patent:
January 12, 1999
Nissan Motor Co., Ltd., Riken Corporation
Abstract: A pipe coupling is provided having a pair of arcuate housings each provided with a crescent groove and a crescent protrusion formed on an abutting end surface of the arcuate housings in the positions which is symmetrical to each other around a vertical axis and is offset from a transverse central axis. When the arcuate housings are tightened by bolts and nuts, the crescent protrusion is inserted into the crescent groove, thereby causing skewed movement of the arcuate housings around the vertical central axis of the pipe coupling in adverse directions to the predetermined angular positions. Thus, upon completion of tightening by the bolts, excessive tightening by the bolt is prevented due to mutual contact of the abutting end surfaces of the arcuate housings.
Abstract: A joint structure, constituting a camshaft, of a metallic tubular member and metallic annular cam defining parts, the annular parts being joined to the outer periphery of the tubular member. Each of the annular parts has around its inner periphery at least one serrated portion which cuts into the outer periphery of the tubular member when they are joined, the annular part also having a planar portion facing another portion of the tubular member in such a manner that substantially no pressure is exerted on the planar portion of the annular part.
October 25, 1985
Date of Patent:
November 4, 1986
Toshiyasu Sugiuchi, Susumu Aoyama, Toshio Yoshida