Patents Assigned to Riker Laboratories, Inc.
  • CRC-free medicinal aerosol formulations of 1,1,1,2-tetrafluoroethane (134A) with polar adjuvant
    Patent number: 6352684
    Abstract: A medicinal aerosol formulation including 0.01-5% medicament, at least 50% by weight 1,1,1,2-tetrafluoroethane (134a), less than 5% surface active agent, and at least one compound having higher polarity than 1,1,1,2-tetrafluoroethane, and which is free of chlorofluorocarbons and propellants CHClF2, CH2F2 and CF3CH3.
    Type: Grant
    Filed: April 28, 1998
    Date of Patent: March 5, 2002
    Assignee: Riker Laboratories Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Medicinal aerosol formulations
    Patent number: 5776434
    Abstract: A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: January 16, 1997
    Date of Patent: July 7, 1998
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Medicinal aerosol formulations
    Patent number: 5766573
    Abstract: A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: January 16, 1997
    Date of Patent: June 16, 1998
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • 1H-imidazo?4,5-c!quinolin-4-amines
    Patent number: 5756747
    Abstract: Novel 1H-imidazo?4,5-c!quinolin-4-amines are disclosed. The compounds function as antiviral agents and they are potential synthetic intermediates in the preparation of known antiviral agents and labeled known antiviral agents. Processes for the preparation of the compounds, methods for their antiviral use, and methods of inducing interferon biosynthesis, are also described.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: May 26, 1998
    Assignee: Riker Laboratories, Inc.
    Inventor: John F. Gerster
  • Bioadhesive composition and patch
    Patent number: 5750134
    Abstract: A bioadhesive composition that adheres suitably to a mucosal surface and is capable of delivering drugs in sustained fashion, and a patch comprising the bioadhesive composition. Methods of using and processes for preparing the bioadhesive composition are also described.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: May 12, 1998
    Assignee: Riker Laboratories, Inc.
    Inventors: Matthew T. Scholz, Robert A. Scherrer, Nelda M. Marecki, Yen-Lane Chen, Joan K. Barkhaus
  • Bioadhesive composition and patch
    Patent number: 5750136
    Abstract: A bioadhesive composition that adheres suitably to a mucosal surface and is capable of delivering drugs in sustained fashion, and a patch comprising the bioadhesive composition. Methods of using and processes for preparing the bioadhesive composition are also described.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: May 12, 1998
    Assignee: Riker Laboratories, Inc.
    Inventors: Matthew T. Scholz, Robert A. Scherrer, Nelda M. Marecki, Yen-Lane Chen, Joan K. Barkhaus
  • Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo?4,5-C!quinolin-4-amine
    Patent number: 5736553
    Abstract: Pharmaceutical formulations and adhesive-coated sheet materials for the topical and/or transdermal delivery of 1-isobutyl-1H-imidazo?4,5-c!-quinolin-4-amine, including creams, ointments and pressure-sensitive adhesive compositions. Pharmacological methods of using the formulations and the adhesive-coated sheet materials of the invention in the treatment of viral infections.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: April 7, 1998
    Assignee: Riker Laboratories, Inc.
    Inventors: Steven M. Wick, Helen Jensen Schultz, Gregory R. Nelson, Amit K. Mitra, Stephen M. Berge
  • Medicinal aerosol formulations
    Patent number: 5720940
    Abstract: A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: February 24, 1998
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Medicinal aerosol formulations
    Patent number: 5695743
    Abstract: A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: March 4, 1993
    Date of Patent: December 9, 1997
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Medicinal aerosol formulations
    Patent number: 5683677
    Abstract: A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: November 4, 1997
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Medicinal aerosol formulations
    Patent number: 5681545
    Abstract: A self-propelling aerosol formulation which may be free from CFC's comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: October 28, 1997
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Medicinal aerosol formulations
    Patent number: 5674473
    Abstract: A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: October 7, 1997
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Medicinal aerosol formulations
    Patent number: 5605674
    Abstract: A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: February 25, 1997
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Process for 1H-imidazo[4,5-C]quinolines
    Patent number: 5602256
    Abstract: A process for the preparation of 1-substituted,4-substituted-1H-imidazo-[4,5-c]quinolines, intermediates in the preparation of such compounds, and processes for the preparation of such intermediates.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: February 11, 1997
    Assignee: Riker Laboratories, Inc.
    Inventors: Jean-Denis Andr e, Daniel Lagin
  • Process for 1H-imidazo[4,5-c]quinolines
    Patent number: 5578727
    Abstract: A process for the preparation of 1-substituted,4-substituted-1H-imidazo-[4,5-c]quinolines, intermediates in the preparation of such compounds, and processes for the preparation of such intermediates.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: November 26, 1996
    Assignee: Riker Laboratories, Inc.
    Inventors: Jean-Denis Andre, Daniel Lagain
  • Substituted Di-T-Butlyphenols useful for inhibiting leukotriene synthesis
    Patent number: 5527824
    Abstract: Substituted Di-T-Butylphenols useful for inhibiting the synthesis of leukotrienes are disclosed.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: June 18, 1996
    Assignee: Riker Laboratories, Inc.
    Inventor: Robert A. Scherrer
  • Substituted di-t-butylphenols
    Patent number: 5498745
    Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an N-methyltetrazolyl substituent, are useful antiallergic agents. Pharmaceutical compositions containing and pharmacological methods of using such compounds are also disclosed, as are synthetic intermediates for preparing such compounds. Certain of the synthetic intermediates also exhibit useful antiallergic activity.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: March 12, 1996
    Assignee: Riker Laboratories, Inc.
    Inventor: Robert A. Scherrer
  • Substituted di-t-butylphenols
    Patent number: 5495043
    Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an N-methyltetrazolyl substituent, are useful antiallergic agents. Pharmaceutical compositions containing and pharmacological methods of using such compounds are also disclosed, as are synthetic intermediates for preparing such compounds. Certain of the synthetic intermediates also exhibit useful antiallergic activity.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: February 27, 1996
    Assignee: Riker Laboratories, Inc.
    Inventor: Robert A. Scherrer
  • Medicinal aerosol formulations
    Patent number: 5439670
    Abstract: A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: July 2, 1993
    Date of Patent: August 8, 1995
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Substituted di-t-butylphenols
    Patent number: 5416113
    Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an N-methyltetrazolyl substituent, are useful antiallergic agents. Pharmaceutical compositions containing and pharmacological methods of using such compounds are also disclosed, as are synthetic intermediates for preparing such compounds. Certain of the synthetic intermediates also exhibit useful antiallergic activity.
    Type: Grant
    Filed: June 22, 1994
    Date of Patent: May 16, 1995
    Assignee: Riker Laboratories, Inc.
    Inventor: Robert A. Scherrer