Abstract: The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
Type:
Grant
Filed:
November 2, 2006
Date of Patent:
August 30, 2011
Assignee:
Rinat Neuroscience Corporation
Inventors:
Joerg Zeller, Kristian T. Poulsen, Yasmina Noubia Abdiche, Jaume Pons, Sierra Leigh Jones Collier, Arnon Rosenthal