Patents Assigned to Riom Laboratoires C.E.R.M. "RL-CERM" S.A.
  • 3-alkoxy-2-(N-pyrrolidino)-N-pyrimidinyl- or -N-pyrazinolpropylamines useful for treatment of cardiovascular disorders
    Patent number: 4762834
    Abstract: The present invention relates to new compounds of the general formula: ##STR1## in which Ar represents thienyl, furyl, pyridyl or an optionally substituted phenyl group,R represents a linear or branched alkyl group with 1 to 7 carbon atoms, andeither X.sub.1 or X.sub.2 represents nitrogen, the other being carbon,and pharmaceutically acceptable acid addition salts thereof, having valuable cardiovascular properties.
    Type: Grant
    Filed: August 20, 1986
    Date of Patent: August 9, 1988
    Assignee: Riom Laboratoires C.E.R.M. "Rl-Cerm", S.A.
    Inventors: Michel Combourieu, Jacques A. L. Simond, Andre J. C. Monteil
  • 2-(N-pyrrolidino)-3-isobutoxy-n-substituted-phenyl-n-benzyl-propylamines, their preparation and pharmaceutical use
    Patent number: 4645778
    Abstract: Compounds of the formula: ##STR1## in which X represents one or two radicals selected from halogen, hydroxyl, alkoxy, alkyl, trifluoromethyl or methylenedioxy radicals, and their pharmaceutically acceptable salts, which may be used in the treatment of cardiovascular disturbances such as angina pectoris, hypertension and rhythmic disorders.
    Type: Grant
    Filed: September 27, 1984
    Date of Patent: February 24, 1987
    Assignee: Riom Laboratoires C.E.R.M. "RL-Cerm"S.A.
    Inventors: Andre J. Monteil, Jacques A. Simond, Michel Combourieu
  • 3-Alkoxy-2-(N-pyrolidino)-N-pyridyl-N-furyl(or thienyl) methyl-pyropyl amines useful as calcium antagonists
    Patent number: 4555514
    Abstract: The present invention relates to new compounds of the general formula: ##STR1## in which X represents oxygen or sulphur and R represents a linear or branched alkyl group with 1 to 7 carbon atoms,and pharmaceutically acceptable acid addition salts thereof, having valuable cardiovascular properties.
    Type: Grant
    Filed: January 9, 1985
    Date of Patent: November 26, 1985
    Assignee: Riom Laboratoires C.E.R.M. "RL-CERM" S.A.
    Inventors: Michel Combourieu, Jacques A. L. Simond, Andre J. Monteil