Abstract: A strawberry plant extract, an extraction method and a novel use thereof are disclosed. The extraction method comprises: darkly incubating a strawberry plant between the anthesis stage and the first harvest stage, harvesting the strawberry plant with the green-white, white or white-red color of the strawberry fruit, and extracting the strawberry plant with ethanol to obtain the strawberry plant extract. The invention further relates to the use of a strawberry plant extract for the manufacture of a composition, wherein the composition is for inhibiting the secretion of cell promoting inflammatory mediators.