Abstract: A drug for treatment of dental caries, comprising an active principle, namely, a mixture of sodium monofluorophosphate and an anticarious preparation obtained by treating osseous tissue with a diluted mineral acid till a complete dissolution of mineral components and water-soluble proteins contained in the osseous tissue, separating the solution, diluting it with water, adding a stabilizer, i.e., citric acid or its salt, to the solution, and neutralizing and evaporating the solution, which anticarious preparation has the following percentage-by-weight composition:______________________________________ calcium 2-6 sodium 19-23 potassium 0.04-0.18 mineral acid anions 6-10.6 orthophosphoric acid anions 1.5-5.0 water-soluble proteins 1.0-5.0 magnesium 0.05-0.2 trace elements, including fluo- rine, manganese, tin, zinc, and iron 0.01-0.