Abstract: A stimulation device is provided that stimulates breathing to manipulate blood gas concentrations such as SaO2 or PCO2 and thereby treat underlying causes of breathing disorders and heart failure progression. A programmable device is provided for setting diaphragm stimulation waveforms that adjust minute ventilation about a predetermined baseline value. Normal breathing of the subject is observed to establish a baseline reference minute ventilation, and the device is programmed to produce stimulation waveforms that may provide either a decrease or an increase in the patients minute ventilation. The minute ventilation of the subject may be decreased or increased from the baseline level by decreasing or increasing a parameter that changes minute ventilators.
Abstract: A device and method is provided for therapeutic stimulating, augmenting, manipulating and/or controlling breathing, in combination with stimulation of auxiliary respiratory nerves or muscles including the upper airway tract, chest wall muscles or abdominal muscles. Stimulation may be provided, for example, to augment breathing or to prevent closing of the upper airway during therapeutic stimulation. Stimulation may be also provided to the Hypoglossal nerve during exhalation.
Type:
Application
Filed:
January 10, 2012
Publication date:
May 3, 2012
Applicant:
RMX, LLC
Inventors:
Amir J. TEHRANI, David LIGON, Chang LEE, Rose PROVINCE, Amy Michelle GOODMAN
Abstract: A device and method is provided for therapeutic stimulating, augmenting, manipulating and/or controlling breathing, in combination with stimulation of auxiliary respiratory nerves or muscles including the upper airway tract, chest wall muscles or abdominal muscles. Stimulation may be provided, for example, to augment breathing or to prevent closing of the upper airway during therapeutic stimulation. Stimulation may be also provided to the Hypoglossal nerve during exhalation.
Type:
Grant
Filed:
June 29, 2006
Date of Patent:
April 17, 2012
Assignee:
RMX, LLC
Inventors:
Amir J. Tehrani, David Ligon, Chang Lee, Rose Province, Amy Michelle Goodman
Abstract: A device and method is provided for biasing lung volume by electrically stimulating tissue associated with the diaphragm or phrenic nerve at a low level.
Type:
Application
Filed:
June 27, 2011
Publication date:
March 1, 2012
Applicant:
RMX, LLC
Inventors:
Amir J. TEHRANI, David LIGON, Chang LEE, Rose PROVINCE, Amy Michelle GOODMAN
Abstract: A device and method is provided for biasing lung volume by electrically stimulating tissue associated with the diaphragm or phrenic nerve at a low level.
Type:
Grant
Filed:
October 31, 2007
Date of Patent:
February 14, 2012
Assignee:
RMX, LLC
Inventors:
Amir J. Tehrani, Rose Province, David Ligon, Chang Lee, Amy Michelle Goodman
Abstract: A device and method for treating a subject is provided where electrical stimulation may be separately provided to each hemidiaphragm to cause diaphragm contraction. Fatigue may be avoided among other possible benefits. Each hemidiaphragm may also be stimulated with different stimulation parameters. Stimulation may be smoothly transitioned between hemidiaphragms. Such stimulation may provide an increase in functional residual capacity or other therapeutic effects.
Type:
Application
Filed:
May 31, 2011
Publication date:
September 22, 2011
Applicant:
RMX, LLC
Inventors:
Amir J. TEHRANI, Rose PROVINCE, David LIGON, Amy GOODMAN, Chang LEE, Drew HOFFMANN
Abstract: A device and method is provided for controlling breathing of a subject by electrically stimulating tissue associated with the diaphragm or phrenic nerve of the subject.
Type:
Grant
Filed:
November 10, 2005
Date of Patent:
July 12, 2011
Assignee:
RMX, LLC
Inventors:
Amir J. Tehrani, David Ligon, Chang Lee, Rose Province, Amy Michelle Goodman
Abstract: A device and method is provided for biasing lung volume by electrically stimulating tissue associated with the diaphragm or phrenic nerve at a low level.
Type:
Grant
Filed:
November 10, 2005
Date of Patent:
June 28, 2011
Assignee:
RMX, LLC
Inventors:
Amir J. Tehrani, David Ligon, Chang Lee, Rose Province, Amy Michelle Goodman
Abstract: A method for treating a patient is provided where a sensed cardiac rhythm is used to adjust electrical stimulation that is used to activate a diaphragm to cause contraction. A cardiac rhythm management device in combination with a diaphragm stimulation device is also provided which includes a cardiac stimulation device configured to provide stimulation to control cardiac rhythm of a subject; and an electrical stimulation device configured to provided electrical stimulation to a subject to activate a diaphragm to increase functional residual capacity of the subject.
Type:
Application
Filed:
April 23, 2008
Publication date:
November 20, 2008
Applicant:
RMX, LLC
Inventors:
Amir J. Tehrani, Rose Province, Chang Lee, David Ligon
Abstract: A cardiovascular treatment assembly is provided including a cardiac rhythm management device and an electrical stimulation device configured to elicit a diaphragm contraction to thereby treat heart failure.