Abstract: The present invention relates to a cellular therapeutic agent for treating urinary incontinence, and more particularly to a cellular therapeutic agent for treating urinary incontinence, which contains stem cells derived from the decidua of the placenta or menstrual fluid or stem cells derived from adipose. The decidua-derived stem cells or adipose-derived stem cells show the effects of increasing leak point pressure and urethral sphincter contractility, and thus are useful as an agent for treating urinary incontinence.

Abstract: The present invention relates to a composition for increasing the milk production of livestock, containing Artemisia capillaris as an active ingredient. More specifically, relates to a composition and a feed additive for increasing the milk production of cows, containing Artemisia capillaris as an active ingredient, and a composition and a feed additive for reducing the number of somatic cells in livestock milk, containing Artemisia capillaris as an active ingredient. The composition can increase milk production of animals, and, in addition, can reduce the number of somatic cells in milk being produces, thus enabling production of good quality milk.

Abstract: The present invention relates to a medium for culturing mesenchymal stem cells, and more particularly to a medium composition for culturing mesenchymal stem cells, which contains basal medium, L-ascorbic acid 2-phosphate, fetal bovine serum, basic fibroblast growth factor (b-FGF), non-essential amino acids (NEAAs), insulin, N-acetyl-L-cysteine, calcium chloride, and hydrocortisone, and a method of culturing mesenchymal stem cells using the same. According to the present invention, a number of mesenchymal stem cells required for stem cell therapy can be obtained in a short time, and the ability of mesenchymal stem cells to differentiate is improved so that they are useful for stem cell therapy.

Abstract: The present invention relates to the ability of adipose tissue-derived adult stem cells to migrate, and more particularly to the novel use of adipose tissue-derived adult stem cells primed with a specific chemokine or growth factor and their specific secretory products, which more effectively migrate to a disease site in vivo. The inventive composition containing either adipose-derived adult stem cells or adipose tissue-derived adult stem cells primed with a specific chemokine or growth factor can be administered by a simple method such as intravenous administration and are able to induce the targeting of the stem cells to a disease site. Thus, the composition is useful as a cell therapeutic agent.

Abstract: The present invention relates to a cellular therapeutic agent for treating urinary incontinence, and more particularly to a cellular therapeutic agent for treating urinary incontinence, which contains stem cells derived from the decidua of the placenta or menstrual fluid or stem cells derived from adipose. The decidua-derived stem cells or adipose-derived stem cells show the effects of increasing leak point pressure and urethral sphincter contractility, and thus are useful as an agent for treating urinary incontinence.

Abstract: The present invention relates to a medium for culturing mesenchymal stem cells, and more particularly to a medium composition for culturing mesenchymal stem cells, which contains basal medium, L-ascorbic acid 2-phosphate, fetal bovine serum, basic fibroblast growth factor (b-FGF), non-essential amino acids (NEAAs), insulin, N-acetyl-L-cysteine, calcium chloride, and hydrocortisone, and a method of culturing mesenchymal stem cells using the same. According to the present invention, a number of mesenchymal stem cells required for stem cell therapy can be obtained in a short time, and the ability of mesenchymal stem cells to differentiate is improved so that they are useful for stem cell therapy.

Abstract: The present invention relates to an antiviral composition comprising an Alnus japonica extract, more specifically, relates to a method for preparing high activated anti-influenza viral composition, which comprises an extract of the bark or stem of Alnus japonica, and an anti-influenza viral composition comprising the extract. An extract of the bark or stem of Alnus japonica according to the present invention has low toxicity to normal cells, while having an excellent antiviral effect even when administered at low concentration and thus the composition comprising the Alnus japonica extract can be used effectively in preventing and treating influenza viral infection.

Abstract: The present invention relates to a method for isolating and culturing adult stem cells derived from human amniotic membrane in high yield, and more particularly to a method for obtaining a large amount of adult stem cells, the method comprising obtaining amniotic epithelial cells from human amniotic tissue in high yield by treatment with dithiothreitol (DTT) and a low concentration of trypsin and culturing the amniotic epithelial cells in a medium containing a Rho-associated kinase inhibitor. The human amniotic epithelial cell-derived stem cells are easily extracted compared to existing therapeutic stem cells such as umbilical cord blood stem cells and bone marrow stem cells, the yield and proliferation thereof are significantly increased by DTT treatment, the addition of the ROCK inhibitor or the replacement of medium. Thus, the method can be used to efficiently prepare adult stem cells.

Abstract: The present invention relates to a diaryl hepatonoid-based compound of formula (1) having viral inhibitory activity; its pharmaceutically acceptable salt; or a hydrate, a solvate or a prodrug of any of the foregoing, and a pharmaceutical composition comprising the same, and the use thereof therapeutic agents. The diaryl hepatonoid-based compounds according to present invention have an excellent effect of inhibiting viral activity, and thus will be useful as therapeutic agents against virus-related diseases.

Abstract: The present invention relates to a composition for increasing the milk production of livestock, containing Artemisia capillaris as an active ingredient. More specifically, relates to a composition and a feed additive for increasing the milk production of cows, containing Artemisia capillaris as an active ingredient, and a composition and a feed additive for reducing the number of somatic cells in livestock milk, containing Artemisia capillaris as an active ingredient. The composition can increase milk production of animals, and, in addition, can reduce the number of somatic cells in milk being produces, thus enabling production of good quality milk.

Abstract: The present invention relates to antioxidative and hepatoprotective compositions, and more particularly to antioxidative and hepatoprotective compositions comprising diarylheptanoid compounds from Alnus japonica. The diarylheptanoid compounds from Alnus japonica include a compound selected from the group consisting of alusenone 1a, alusenone 1b, hirsutenone, hirsutanonol, oregonin, alnuside A, alnuside B, rubranoside B and rubranoside C. The antioxidative and hepatoprotective compositions have excellent antioxidative and hepatoprotective activities while having no side effects, and thus are useful for the prevention and treatment of oxidation-associated diseases and liver diseases.

Abstract: The present invention relates to the ability of adipose tissue-derived adult stem cells to migrate, and more particularly to the novel use of adipose tissue-derived adult stem cells primed with a specific chemokine or growth factor and their specific secretory products, which more effectively migrate to a disease site in vivo. The inventive composition containing either adipose-derived adult stem cells or adipose tissue-derived adult stem cells primed with a specific chemokine or growth factor can be administered by a simple method such as intravenous administration and are able to induce the targeting of the stem cells to a disease site. Thus, the composition is useful as a cell therapeutic agent.

Abstract: The present invention relates to a method of proliferating follicular stem cells in high yield, and more particularly, to a method of proliferating follicular stem cells in large amounts by culturing the cells using a specific medium containing a specific concentration of a Rho-associated kinase (ROCK) inhibitor and to a medium which is used in the method.

Abstract: The present invention relates to a composition for preventing or treating cancer, which contains one or more selected from the group consisting of human adult stem cells and their secretory products, and to a method of preventing or treating cancer using the same. Particularly, the invention relates to the use of adult stem cells that exhibit the effect of preventing or treating cancer by activating the immune system. The human adult stem cells of the invention are administered by a simple method such as intravenous injection and are highly valuable as a cell therapeutic agent for treating various cancer (tumor) diseases. Thus, the adult stem cells will be highly useful in anticancer studies.

Abstract: The present invention relates to an antiviral composition comprising an Alnus japonica extract, more specifically, relates to a method for preparing high activated anti-influenza viral composition, which comprises an extract of the bark or stem of Alnus japonica, and an anti-influenza viral composition comprising the extract. An extract of the bark or stem of Alnus japonica according to the present invention has low toxicity to normal cells, while having an excellent antiviral effect even when administered at low concentration and thus the composition comprising the Alnus japonica extract can be used effectively in preventing and treating influenza viral infection.

Abstract: Human adipose tissue-derived multipotent adult stem cells are provided, which are characterized by the ability to be maintained in an undifferentiated state for a long period of time by forming spheres and which have high proliferation rates. Also provided are methods for isolating and maintaining the adult stem cells, and methods for differentiating the multipotent adult stem cells into nerve cells, fat cells, cartilage cells, osteogenic cells, muscle cells, endothelial cells, hepatic cells and insulin-releasing pancreatic ?-cells. Also provided are cellular therapeutic agents for treating osteoarthritis, osteoporosis, nerve disease, diabetes and for forming breast tissue, which contain differentiated cells or the adult stem cells.

Abstract: The present invention relates to antioxidative and hepatoprotective compositions, and more particularly to antioxidative and hepatoprotective compositions comprising diarylheptanoid compounds from Alnus japonica. The diarylheptanoid compounds from Alnus japonica include a compound selected from the group consisting of alusenone 1a, alusenone 1b, hirsutenone, hirsutanonol, oregonin, alnuside A, alnuside B, rubranoside B and rubranoside C. The antioxidative and hepatoprotective compositions have excellent antioxidative and hepatoprotective activities while having no side effects, and thus are useful for the prevention and treatment of oxidation-associated diseases and liver diseases.

Abstract: The present invention relates to a cellular therapeutic agent for treating urinary incontinence, and more particularly to a cellular therapeutic agent for treating urinary incontinence, which contains stem cells derived from the decidua of the placenta or menstrual fluid or stem cells derived from adipose. The decidua-derived stem cells or adipose-derived stem cells show the effects of increasing leak point pressure and urethral sphincter contractility, and thus are useful as an agent for treating urinary incontinence.

Abstract: The present invention relates to an antiviral composition comprising an Alnus japonica extract, more specifically, relates to a method for preparing high activated anti-influenza viral composition, which comprises an extract of the bark or stem of Alnus japonica, and an anti-influenza viral composition comprising the extract. An extract of the bark or stem of Alnus japonica according to the present invention has low toxicity to normal cells, while having an excellent antiviral effect even when administered at low concentration and thus the composition comprising the Alnus japonica extract can be used effectively in preventing and treating influenza viral infection.

Abstract: The present invention relates to a composition for increasing the milk production of livestock, containing Artemisia capillaris as an active ingredient. More specifically, relates to a composition and a feed additive for increasing the milk production of cows, containing Artemisia capillaris as an active ingredient, and a composition and a feed additive for reducing the number of somatic cells in livestock milk, containing Artemisia capillaris as an active ingredient. The composition can increase milk production of animals, and, in addition, can reduce the number of somatic cells in milk being produced, thus enabling production of good quality milk.