Patents Assigned to Robert Bosch Gesellschaft fur Medizinische Forschung (RBMF)
  • Diagnostic methods for therapeutic compounds and methods for monitoring azathioprine therapy
    Patent number: 7524851
    Abstract: The present invention provides diagnostic methods for predicting therapeutic efficacy in an individual being treated for an autoimmune or an inflammatory disease. In addition, the present invention also provides novel methods for monitoring azathioprine therapy or optimizing clinical responsiveness to azathioprine therapy in an individual by measuring 6-thioguanosine nucleotide levels in a sample from the individual.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: April 28, 2009
    Assignee: Robert Bosch Gesellschaft fur Medizinische Forschung (RBMF)
    Inventors: Markus F. Neurath, Matthias Schwab