Abstract: The tricyclic dihydropyridazinone derivatives having formula I ##STR1## are endowed with interesting hypotensive, vasodilating, antiaggregant, antithrombotic and cytoprotective properties and are therefore useful in human or veterinary medicine.
Type:
Grant
Filed:
July 22, 1985
Date of Patent:
September 8, 1987
Assignee:
Boehringer Biochemia Robin, S.p.A.
Inventors:
Giorgio Cignarella, Carmelo A. Gandolfi, Odoardo Tofanetti, Piervitto Cipolla, Sergio Tognella
Abstract: A completely tryptophan-free dietetic supplement based on amino acids, which has an effect on sleep, comprising at least L-isoleucine (4-16%), L-leucine (9-27%), L-lysine (7-20%), L-methionine (9-27%), L-phenylalanine (9-27%), L-threonine 4-12%) and L-valine (6-19%). It can also comprise other amino acids and substances which contribute calories, minerals and vitamins, as well as the vehicles required by the form of presentation provided for. It can be included in prepackaged foods for meals, for instance normocaloric meals and for infusions.
Abstract: Benzamides of formula I ##STR1## are described, in which R=CH.sub.3, Cl or COOCH.sub.3 ; R' is a member selected from the group of dialkylamine, pyrrolidine, piperidine, and morpholine radicals. CH.sub.2 R' is in position ortho, meta, or para with respect to the carbonyl group; and their salts thereof with pharmaceutically acceptable acids are described. The novel compounds exhibit local anaesthetic and antiarrhythmic activity.
Type:
Grant
Filed:
November 18, 1980
Date of Patent:
December 15, 1981
Assignee:
B.B.R. Boehringer Biochemia Robin S.p.A.