Patents Assigned to Roche Molecurlar Systems, Inc.
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20120208240
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: July 11, 2011
    Publication date: August 16, 2012
    Applicant: Roche Molecurlar Systems, Inc.
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers