Abstract: A method of making hand-actuated retention catheter 5 is disclosed. The retention catheter includes a tube 12, an overcoat layer 14 encircling the tube 12 and a cavity 16 interposed between the tube 12 and the overcoat layer 14. The cavity 16 encircles the tube and includes a bulbous balloon portion 24 and an enlarged fluid reservoir portion 22 interconnected and separated by a catheter sleeve portion 26 which has a narrowed outside diameter. The expandable balloon portion 24 can be expanded by compressing the fluid reservoir portion 22. A variabale thickness coating of bond-preventing agent is formed on a polymeric structure prior to dipping in a polymeric material to form the overcoat layer.

Abstract: A method of shaping polymeric structures by coating a support structure with a bond-preventing agent to attain a particular shape and subsequently coating the shaped structure of the bond-preventing agent with a polymeric bonding composition is provided. Such shaped polymeric structures can have one or more cavities which can be fluid-filled or gel-filled. Also provided is a hand-actuating retention female urinary catheter having an inner tube and an outer overcoat layer encircling the tube with an elastomeric collar with a shroud. A cavity containing a fluid is interposed between the tube and the overcoat layer. The cavity includes a balloon portion and a reservoir portion. The shroud encircles the reservoir section to inhibit the ballooning of the reservoir section when the reservoir section is squeezed to force fluid from the reservoir portion to the balloon portion through the sleeve portion of the cavity. The overcoat layer and the collar with a shroud are made of soft resilient material.

Abstract: Methods of making sustained release bactericidal cannulas or catheters through which aqueous biological fluids can pass. The bactericidal cannula for catheter including a tube having an inner surface, defining and interior lumen, and an outer surface. The tube has a polymeric matrix and antibacterial agent residing within at least a portion of the polymeric matrix. The polymeric matrix includes cured silicon rubber and the antibacterial agent is a finely divided nitrofuran compound which is soluble in water and effective to prevent proliferation of certain bacteria in an otherwise growth supporting aqueous environment when dissolved in the aqueous environment to the limit of its solubility therein at 37.degree. C. The solubility of the nitrofuran compound is about 0.2% by weight or less at a pH of about 6 and a temperature of about 25.degree. C.

Abstract: An external urinary catheter having integral adhesive means. The external urinary catheter includes (a) a single tubular sheath having a unitary construction made of silicone rubber, the silicone rubber having an inner surface and an outer surface; and (b) a layer of adhesive material bonded to a first portion of the inner surface; wherein the adhesive material can releasably contact portions of the outer surface such that the inner surface of the silicone rubber sheath can be rolled up on the outer surface thereof so that the adhesive layer on the first portion of the inner surface comes into releasable contact with the portions of the outer surface, and such that the adhesive material on the outer surface will then release any portions of the outer surface with which it has come into contact, while remaining bonded to the inner surface, when the silicone rubber sheath is forcibly unrolled. A method of making an external urinary catheter is also disclosed.

Abstract: A hand-actuated retention catheter 5 is disclosed. The retention catheter includes a tube 12, an overcoat layer 14 encircling the tube 12 and a cavity 16 interposed between the tube 12 and the overcoat layer 14. The cavity 16 encircles the tube and includes a bulbous balloon portion 24 and an enlarged fluid reservoir portion 22 interconnected and separated by a catheter sleeve portion 26 which has a narrowed outside diameter. The expandable balloon portion 24 can be expanded by compressing the fluid reservoir portion 22. Methods of making the hand-actuated retention catheter and methods of using the same are also disclosed.

Abstract: A condom catheter having a sheath and a smaller diameter tube separated by a cone-shaped transition section with adhesive on the inner surface of the sheath and most of the transition section. The catheter is intended for a male having a recessed penis. The transition section is fastened to the penile tip such that the penile shaft may be pulled from pelvic skin so that the sheath can be unrolled onto the penile shaft so that when the penis recesses back into the pelvic skin, the catheter remains fastened to the penile shaft.

Abstract: An elongated catheter having an interior and an exterior surface, wherein the interior surface defines a lumen passing through the catheter. The catheter further including an enclosed cavity between the interior and exterior surfaces which encircles of the lumen. The cavity having an inner wall and an outer wall, the outer wall being a resilient sleeve which can stretch generally independently of the inner wall. The cavity containing an amount of a suitable lubricating substance effective to permit the resilient sleeve to slide along an outer surface of the inner wall while in lubricated contact therewith when stretched independently of the inner wall and including a bactericidal agent, wherein the inner wall and the outer wall are joined together at distal end proximal ends of the enclosed cavity. The resilient sleeve includes a plurality of micropores which permit the bactericidal agent to diffuse into suitable aqueous environments.

Abstract: A sustained release bactericidal cannula or catheter for residence within a portion of a human body through which aqueous biological fluids can pass. The bactericidal cannula for catheter including a tube having an inner surface, defining and interior lumen, and an outer surface. The tube has a polymeric matrix and antibacterial agent residing within at least a portion of the polymeric matrix. The polymeric matrix includes cured silicon rubber and the antibacterial agent is a finely divided nitrofuran compound which is soluble in water and effective to prevent proliferation of certain bacteria in an otherwise growth supporting aqueous environment when dissolved in the aqueous environment to the limit of its solubility therein at 37.degree. C. The solubility of the nitrofuran compound is preferably about 0.2% by weight or less at a pH of about 6 and a temperature of about 25.degree. C.

Abstract: An external urinary catheter having integral adhesive means. The external urinary catheter includes (a) a single tubular sheath having a unitary construction made of silicone rubber, the silicone rubber having an inner surface and an outer surface; and (b) a layer of adhesive material bonded to a first portion of the inner surface; wherein the adhesive material can releasably contact portions of the outer surface such that the inner surface of the silicone rubber sheath can be rolled up on the outer surface thereof so that the adhesive layer on the first portion of the inner surface comes into releasable contact with the portions of the outer surface, and such that the adhesive material on the outer surface will then release any portions of the outer surface with which it has come into contact, while remaining bonded to the inner surface, when the silicone rubber sheath is forcibly unrolled. A method of making an external urinary catheter is also disclosed.

Abstract: A method of making a balloon catheter. The method includes the steps of providing a tube having an outer surface and a plurality of lumens including first and second lumens, the tube including a first lumen access opening in the outer surface communicating with the first lumen; simultaneously coating a first portion of the outer surface with an amount of a bond preventing agent effective to prevent bonding to the first portion of the outer surface and plugging the first lumen access opening; and subsequently coating a second portion of the outer surface and the coating of bond preventing agent on the first portion of the outer surface with a polymeric bonding composition, wherein a resilient overcoat layer is created which is fixed to and integral with the tube proximate the second portion of the outer surface and free from adherence to the tube proximate the first portion of the outer surface. An alternate embodiment provides a method of mass-producing balloon catheters.

Abstract: An elongated catheter having an interior and an exterior surface, wherein the interior surface defines a lumen passing through the catheter. The catheter further including an enclosed cavity between the interior and exterior surfaces which encircles of the lumen. The cavity having an inner wall and an outer wall, the outer wall being a resilient sleeve which can stretch generally independently of the inner wall. The cavity containing an amount of a suitable lubricating substance effective to permit the resilient sleeve to slide along an outer surface of the inner wall while in lubricated contact therewith when stretched independently of the inner wall, wherein the inner wall and the outer wall are joined together at distal end proximal ends of the enclosed cavity. An automated method for producing the same, including a series of automated dipping steps, is also disclosed.