Patents Assigned to Rorer Italiana S.p.A.
  • Polysaccharide having antiinflammatory and platelet antiaggregation activity
    Patent number: 4507286
    Abstract: The extraction is described of a substance endowed with antiinflammatory and platelet antiaggregation activity, starting from the juice of plants of the species Ananas, Bromelia, Karatas, etc. of the family Bromeliaceae, or extractable from their derivatives such as bromelain. The extraction may be made by means of thermo-coagulation or precipitation by trichloracetic acid, starting both from raw juices obtained from their roots or from the fruits, and from previously isolated bromelain.
    Type: Grant
    Filed: March 17, 1983
    Date of Patent: March 26, 1985
    Assignee: Rorer Italiana, S.P.A.
    Inventor: Massimiliano Vellini
  • Steroid derivatives
    Patent number: 4081541
    Abstract: The present invention is concerned with new derivatives of the cortisone series having in particular a corticoidal, anti-phlogistic and anti-anaphylactic activity.The compounds of the present invention are represented by the formula: ##STR1## in which: St is a radical selected from 9-chloro-11.beta.,17,21-trhihydroxy-16.beta.-methyl-pregna-1,4 diene-3,20 dione and 9-fluoro-11.beta.,17,21 -trihydroxy-16-.alpha.-methyl-pregna-1,4 diene-3,20 dione, the ester linkage being at position 21 of the steroid group.
    Type: Grant
    Filed: December 28, 1976
    Date of Patent: March 28, 1978
    Assignee: Rorer Italiana S.p.A.
    Inventor: Aldo Bertelli
  • Derivatives of aminomethylcyclohexanecarboxylic acid
    Patent number: 4055580
    Abstract: The present invention is concerned with new derivatives of transaminomethylcyclohexanecarboxylic acid, which possess an anti-toxic, anti-hyperlipidic, anti-atherosclerosis, anti-phlogistic and gastroprotective activity.The compounds of the invention are represented by the general formula : ##STR1## in which : R is a group C.sub.n H.sub.2n+n' --CO--n is an integer from 4 to 20,n' is +1, -1, -3 or -5, andR' is hydrogen or an alkyl group having 1 to 6 carbon atoms.
    Type: Grant
    Filed: August 22, 1975
    Date of Patent: October 25, 1977
    Assignee: Rorer Italiana S.p.A.
    Inventor: Aldo Bertelli
  • Steroid derivatives
    Patent number: 4011317
    Abstract: The present invention is concerned with new derivatives of the cortisone series having in particular a cortisonelike action of the steroid anti-inflammatory type.The compounds of the present invention are represented by the general formula: ##STR1## in which: St is a steroid group of the pregnane, pregnene, or pregnadiene series, the ester linkage being at position 21 of the steroid group.
    Type: Grant
    Filed: August 22, 1975
    Date of Patent: March 8, 1977
    Assignee: Rorer Italiana S.p.A.
    Inventor: Aldo Bertelli
  • Bis-2,6-[N-(.alpha.-benzoylthiopropionyl)glycyloxymethyl]pyridine
    Patent number: 3978070
    Abstract: This invention relates to 2,6-bis-[N-(.alpha.-benzoylthiopropionyl)glycyloxymethyl]pyridine having the formula: ##EQU1## This compound possesses a protecting activity, particularly at the level of the liver, against lesions induced by toxic or infectious agents and, generally, against agents which induce hepatic and circulatory disorders and also against atherosclerotic or inflammatory lesions.
    Type: Grant
    Filed: September 9, 1975
    Date of Patent: August 31, 1976
    Assignee: Rorer Italiana S.p.A.
    Inventor: Aldo Bertelli