Patents Assigned to Rorer Pharmaceutical Corp.
  • Patent number: 5002771
    Abstract: Disclosed are rectal and vaginal suppository formulations comprising calcitonin and caprylic acid monoglyceride in a pharmaceutically acceptable suppository vehicle.
    Type: Grant
    Filed: February 3, 1989
    Date of Patent: March 26, 1991
    Assignee: Rorer Pharmaceutical Corp.
    Inventors: Abdur R. Purkaystha, Gary G. Gazdick, Jay E. Dorrell, Keith C. Mozzone, Howard J. Levin
  • Patent number: 4920227
    Abstract: Certain specific substituted benzobicyclic carboxamides and their valuable use as 5-HT3 antagonists having CNS and gastric prokenetic activity void of any significant D.sub.2 receptor binding activity are disclosed.
    Type: Grant
    Filed: November 29, 1988
    Date of Patent: April 24, 1990
    Assignee: Rorer Pharmaceutical Corp.
    Inventors: Jeffrey C. Pelletier, Raymond D. Youssefyeh, Henry F. Campbell
  • Patent number: 4920132
    Abstract: This invention relates to certain quinoline-diaryl compounds and their use as leukotriene D.sub.4 antagonists for the treatment of hypersensitive disorders.
    Type: Grant
    Filed: November 3, 1987
    Date of Patent: April 24, 1990
    Assignee: Rorer Pharmaceutical Corp.
    Inventors: Fu-chi Huang, Robert A. Galemmo, Jr., Henry F. Campbell
  • Patent number: 4920133
    Abstract: This invention relates to certain quinoline-diaryl compounds and their use as leukotriene D.sub.4 antagonists for the treatment of hypersensitive disorders.
    Type: Grant
    Filed: November 3, 1987
    Date of Patent: April 24, 1990
    Assignee: Rorer Pharmaceutical Corp.
    Inventors: Fu-chi Huang, Robert A. Galemmo, Jr., Henry F. Campbell
  • Patent number: 4920131
    Abstract: This invention relates to quinolinyl compounds of the general formula: ##STR1## and the use of these compounds as pharmacological agents which are lipoxygenase inhibitors and/or leukotriene antagonists possessing anti-inflammatory and anti-allergic properties and their pharmaceutical compositions and processes for this preparation.
    Type: Grant
    Filed: June 21, 1988
    Date of Patent: April 24, 1990
    Assignee: Rorer Pharmaceutical Corp.
    Inventors: Fu-Chi Huang, Robert A. Galemmo, Jr., Henry F. Campbell
  • Patent number: 4920219
    Abstract: Certain specific substituted azabicyclic carboxiamides and their valuable use as 5-HT3 antagonists having CNS and gastric prokenetic activity void of any D.sub.2 receptor binding properties are disclosed.
    Type: Grant
    Filed: November 29, 1988
    Date of Patent: April 24, 1990
    Assignee: Rorer Pharmaceutical Corp.
    Inventors: Jeffrey C. Pelletier, Raymond D. Youssefyeh, Henry F. Campbell
  • Patent number: 4918081
    Abstract: This invention relates to quinolinyl compounds of the general formula: ##STR1## and the use of these compounds as pharmacological agents which are lipoxygenase inhibitors and/or leukotriene antagonists possessing anti-inflammatory and anti-allergic properties and their pharmaceutical compositions and processes for this preparation.
    Type: Grant
    Filed: June 20, 1988
    Date of Patent: April 17, 1990
    Assignee: Rorer Pharmaceutical Corp.
    Inventors: Fu-Chi Huang, Robert A. Galemmo, Jr., Henry F. Campbell
  • Patent number: 4900754
    Abstract: Disclosed are novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula ##STR1## and the corresponding ring-opened hydroxy acids derived therefrom and pharmaceutically acceptable salts thereof.Pharmaceutical compositions containing said compounds and method of inhibiting the biosynthesis of cholesterol therewith are also disclosed.
    Type: Grant
    Filed: March 27, 1989
    Date of Patent: February 13, 1990
    Assignee: Rorer Pharmaceutical Corp.
    Inventors: John R. Regan, Kent W. Neuenschwander
  • Patent number: 4748272
    Abstract: This invention relates to new lipoxygenase inhibitors possessing anti-inflammatory and anti-allergic properties. The present new compounds are of the formula: ##STR1## and salts thereof; whereinAr is phenyl, naphthyl or sulfur, oxygen or nitrogen heterocyclic;X is O, S, NR.sub.5, or a chemical bond;R is H, lower alkoxy, aryloxy, hydroxy, lower alkyl, aryl or lower aralkyl;R.sub.1 and R.sub.2 are independently hydrogen, hydroxy, lower alkoxy, lower alkyl, aryl, aryloxy, lower aralkyl, lower aralkoxy, formyl, lower alkanoyl, benzoyl, and lower aralkanoyl;R.sub.3 and R.sub.4 are independently hydrogen, halogen, hydroxy, lower alkoxy, aryloxy, lower aralkoxy, trifluoromethyl, lower carbalkoxy, carboxy, cyano, nitro, lower alkyl, lower alkenyl, lower alkynyl, aryl or lower aralkyl;R.sub.5 is H, lower alkyl, lower aralkyl or aryl;R.sub.6 is hydroxy or hydroxy-substituted lower alkyl;n and m are independently 0, 1, 2 or 3.
    Type: Grant
    Filed: August 1, 1986
    Date of Patent: May 31, 1988
    Assignee: Rorer Pharmaceutical Corp.
    Inventor: Raymond D. Youssefyeh