Patents Assigned to Ross Southern Laboratories
  • Serodiagnosis of Lyme disease by use of two recombinant proteins in ELISA
    Patent number: 10802022
    Abstract: Two Borrelia burgdorferi recombinant proteins were expressed in E. coli. These two proteins were generated from (a) the full length dbpA gene combined with the invariable region 6 of the VlsE gene (dbpA/C6), and (b) the full length OspC gene combined with the coding sequence for amino acids 1-121 of the E. coli maltose binding protein gene (OspC/MBP). Methods of using these recombinant proteins for detecting anti-Borrelia burgdorferi antibodies in patient sera and diagnosis of Lyme Disease are described.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: October 13, 2020
    Assignee: Ross Southern Laboratories
    Inventors: Gary L. Bradshaw, R. Kelley Thueson, Todd Joseph Uriona