Abstract: In order to separate viruses from protein solutions, particles of a solid phase are suspended in said protein solution. The solid phase is an adsorbent chosen from the group kieselguhr, silicic acid, clay minerals, metal hydroxide or oxihydrate, cellulose, perlite, and water insoluble synthetic polymers. Subsequently the solid phase together with the viruses that have adsorbed to it is separated from the fluid phase. The protein solution is brought into contact at least once with the solid phase for at least 10 minutes during which time a suspension is formed; subsequently the solid phase is separated from the liquid phase.

Abstract: In a process for the inactivation of enveloped viruses in a biological fluid buckminsterfullerene (C.sub.60) is used as a photosensitizer. In a photodynamic processes singlet oxygen is generated which is the active agent for the inactivation of viruses present in the fluid. The process comprises the steps of (a) contacting of a solution or dispersion of material derived from the human body or from the bodies of animals with buckminsterfullerene as a photosensitizer, of (b) saturating the solution or dispersion with oxygen; and of (c) irradiating the solution or dispersion with visible or invisible light for activating the oxygen into the singlet state until viruses contained in the solution or dispersion are inactivated. This virus inactivation is specially suitable for protein solutions, e.g. bovine serum albumin, BSA or plasma products of human origin.

Abstract: In order to separate viruses from protein solutions, particles of a solid phase are suspended in said protein solution. The solid phase is an adsorbent chosen from the group kieselguhr, silicic acid, clay minerals, metal hydroxide or oxihydrate, cellulose, perlite, and water insoluble synthetic polymers. Subsequently the solid phase together with the viruses that have adsorbed to it is separated from the fluid phase. The protein solution is brought into contact at least once with the solid phase for at least 10 minutes during which time a suspension is formed; subsequently the solid phase is separated from the liquid phase.

Abstract: An anti-D immunoglobulin G-preparation is produced in high-yield from human plasma containing anti-D IgG, or a plasma fraction containing an anti-D IgG, in which (A) the plasma, or the plasma fraction, with a pH in the range of pH 3.5 to 6.5 and a conductivity value in the range of 2 to 4 mS/cm, is subjected to ion exchange chromatography with an adsorbent which has carboxymethyl groups as functional groups, the anti-D IgG being bound to the adsorbent, (B) the adsorbent with the bound anti-D IgG is first rinsed with a wash solution at a pH in the range of 5 to 8 and a conductivity value in the range of 2 to 4 mS/cm, and the anti-D IgG is subsequently eluted, and further (C) the eluted anti-D IgG at a pH in the range of 6 to 8 and a conductivity value in the range of 2 to 4 mS/cm is treated with an alkaline adsorbent with ion-exchange characteristics in order to bind undesired components, and finally, the anti-D IgG is concentrated.

Abstract: Apolipoproteins are isolated from human blood plasma fractions which contain apolipoproteins by suspending these fractions in buffer solutions. The suspensions are subsequently incubated with a lower aliphatic alcohol, either with or without an organic solvent. The phase which contains the lipoproteins is separated and concentrated. The products obtained according to the procedure may be used primarily for the treatment of cardiovascular diseases, in particular hypercholesterolemia.