Patents Assigned to ROTOP PHARMAKA GMBH
  • DEUTERATED 7-(3-(4-(2-([18F]FLUOR)ETHOXY)PHENYL)PROPYL)-2-(FURAN-2-YL)-7HPYRAZOLO [4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE DERIVATIVES
    Publication number: 20230095104
    Abstract: A compound of general formula I Residues X1a, X1b, X2a, X2b, X3a, X3b, X4a, X4b, X5a, and X5b each independently are hydrogen or deuterium, with the provision that at least one of residues X1a, X1b, X2a, X2b, X3a, X3b, X4a, X4b, X5a, and X5b is deuterium.
    Type: Application
    Filed: June 22, 2020
    Publication date: March 30, 2023
    Applicants: HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V., ROTOP PHARMAKA GMBH
    Inventors: Thu Hang LAI, Rodrigo TEODORO, Magali TOUSSAINT, Daniel GÜNDEL, Winnie DEUTHER-CONRAD, Sladjana DUKIC-STEFANOVIC, Susann SCHRÖDER, Rares-Petru MOLDOVAN, Peter BRUST
  • Stabilized form of tetrofosmin and its use
    Patent number: 9963473
    Abstract: The present invention provides a stabilized form of Tetrofosmin, which is stable at room temperature as well as in contact with oxygen, and a non-radioactive kit containing a stabilized form of Tetrofosmin for the preparation of a radiopharmaceutical composition in the field of diagnostic radiopharmaceuticals, especially for myocardial perfusion studies in patients with coronary artery diseases and in oncology.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: May 8, 2018
    Assignee: ROTOP Pharmaka GmbH
    Inventor: Eik Schiller
  • STABILIZED FORM OF TETROFOSMIN AND ITS USE
    Publication number: 20160355532
    Abstract: The present invention provides a stabilized form of Tetrofosmin, which is stable at room temperature as well as in contact with oxygen, and a non-radioactive kit containing a stabilized form of Tetrofosmin for the preparation of a radiopharmaceutical composition in the field of diagnostic radiopharmaceuticals, especially for myocardial perfusion studies in patients with coronary artery diseases and in oncology.
    Type: Application
    Filed: January 28, 2015
    Publication date: December 8, 2016
    Applicant: ROTOP PHARMAKA GMBH
    Inventor: Eik SCHILLER
  • Method and Kit for the Production of Particles Labelled with Rhenium-188
    Publication number: 20080219923
    Abstract: Rhenium-188 labeled particles are produced by suspending particles of an organic polymer or a biopolymer in a solution wherein the solution contains a water-soluble tin-II salt and a Re-188 perrhenate salt with a radioactivity of 1,000 MBq to 60,000 MBq and wherein the solution has initially a pH value of pH 1 to pH 3; heating the solution of step a) to 80° C. to 100° C.; and, after 45 minutes to 70 minutes of heating, increasing and adjusting the pH value to a pH value of pH 5 to pH 8.5.
    Type: Application
    Filed: January 27, 2005
    Publication date: September 11, 2008
    Applicant: ROTOP PHARMAKA GMBH
    Inventors: Gerd Wunderlich, Antje Drews