Patents Assigned to Rotta Research Laboratories, S.p.A.
  • Patent number: 5976576
    Abstract: A pharmaceutical composition comprising, as active ingredient, N-4-(1H-tetrazol-5-yl)phenyl-4-(1H-tetrazol-5-yl)benzamide disodium salt (CR 2039, Andolast) or another pharmaceutically-acceptable salt thereof and a flavoring, and optionally including a pharmaceutically-acceptable inert carrier and/or a pharmaceutically-acceptable sweetener, the composition being suitable for administration by oral inhalation.
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: November 2, 1999
    Assignee: Rotta Research Laboratories S.p.A.
    Inventors: Francesco Makovec, Paolo Senin, Lucio Claudio Rovati
  • Patent number: 4769389
    Abstract: New Orginal derivates of D,L-glutamic acid and D,L-aspartic acid are described having the formula: ##STR1## where n is 1 or 2, R.sub.1 is a mono- or di-substituted phenyl group substituted with halogens such as chlorine and fluorine or with a methyl group in the 3 and 4 positions and in which R.sub.2 consists of a linear or branched alkyl group with 4 to 7 carbon atoms (preferably a pentyl group) and R.sub.3 is an alkyl group having 3 to 6 carbon atoms overall and containing an oxygen atom in the form of an either linkage, such as for example the groups 2-ethoxyethyl, 3-methoxypropyl, 3-ethoxypropyl etc. or in the form of a hydroxyl group such as for example 3-hydroxypropyl etc.The compounds have antagonistic activity towards bio-active polypeptides and are usable particularly in the treatment of illnesses of the digestive tract, of the central nervous system and anorexia and of all those affections (for example tumours) in which exogenic or endogenic bio-active polypeptides are involved.
    Type: Grant
    Filed: December 17, 1986
    Date of Patent: September 6, 1988
    Assignee: Rotta Research Laboratories, S.p.A.
    Inventors: Francesco Makovec, Rolando Chiste', Lucio Rovati, Luigi Rovati