Patents Assigned to Royal Holloway and Bedford New College Royal Holloway, University of London
  • Oligomers
    Patent number: 8084601
    Abstract: Molecules are provided for inducing or facilitating exon skipping in forming spliced mRNA products from pre-mRNA molecules in cells. The molecules may be provided directly as oligonucleotides or expression products of vectors that are administered to a subject. High rates of skipping can be achieved. High rates of skipping reduce the severity of a disease like Duchene Muscular Dystrophy so that the disease is more like Becker Muscular Dystrophy. This is a severe reduction in symptom severity and mortality.
    Type: Grant
    Filed: September 10, 2009
    Date of Patent: December 27, 2011
    Assignee: Royal Holloway and Bedford New College Royal Holloway, University of London
    Inventors: Linda Popplewell, Ian Graham, John George Dickson