Abstract: The invention relates to a complexing system comprising two polypeptide helices derived from a SNAP protein; one polypeptide helix derived from syntaxin; one polypeptide helix derived from synaptobrevin or a homolog thereof; and one or more cargo moieties attached to the polypeptide helices, wherein the four polypeptide helices can form a stable SNARE complex. The invention also relates to a method of producing the complexing system and the use of the complexing system.
Type:
Application
Filed:
August 11, 2010
Publication date:
February 17, 2011
Applicants:
MEDICAL RESEARCH COUNCIL, ROYAL HOLOLOWAY AND BEDFORD NEW COLLEGE