Abstract: The present invention relates, in part, to isolated antibodies that specifically interact with and show measurable binding affinity to an epitope of the amyloid-beta (A?) protein. Such antibodies may be used for the modulation of A? activity and/or aggregation or amyloidosis, to study the effects of the A? protein on cell function and, in certain embodiments, for the treatment and/or prevention of a disease or condition associated with A? activity, aggregation, and/or amyloidosis.
Type:
Grant
Filed:
November 8, 2019
Date of Patent:
November 2, 2021
Assignee:
rPeptide LLC
Inventors:
Quentin Florence, Nanda Menon, William Moffitt, Bill Lunsford, III
Abstract: The present invention relates, in part, to isolated antibodies that specifically interact with and show measurable binding affinity to an epitope of the tau protein. Such antibodies may be used for the modulation of tau activity and/or aggregation, to study the effects of the tau protein on cell function and, in certain embodiments, for the treatment and/or prevention of a disease or condition associated with neurodegenerative tauopathy.
Type:
Application
Filed:
January 17, 2019
Publication date:
July 11, 2019
Applicant:
rPeptide LLC
Inventors:
Quentin Florence, Nanda Menon, William Moffitt, Bill Lunsford, III
Abstract: The present invention relates, in part, to isolated antibodies that specifically interact with and show measurable binding affinity to an epitope of the tau protein. Such antibodies may be used for the modulation of tau activity and/or aggregation, to study the effects of the tau protein on cell function and, in certain embodiments, for the treatment and/or prevention of a disease or condition associated with neurodegenerative tauopathy.
Type:
Application
Filed:
February 23, 2016
Publication date:
February 22, 2018
Applicant:
rPeptide LLC
Inventors:
Quentin FLORENCE, Nanda MENON, William MOFFITT, Bill LUNSFORD, III
Abstract: The present invention relates, in part, to isolated antibodies that specifically interact with and show measurable binding affinity to an epitope of the amyloid-beta (A?) protein. Such antibodies may be used for the modulation of A? activity and/or aggregation or amyloidosis, to study the effects of the A? protein on cell function and, in certain embodiments, for the treatment and/or prevention of a disease or condition associated with A? activity, aggregation, and/or amyloidosis.
Type:
Application
Filed:
February 23, 2016
Publication date:
February 22, 2018
Applicant:
rPeptide LLC
Inventors:
Quentin FLORENCE, Nanda MENON, William MOFFITT, Bill LUNSFORD, III