Patents Assigned to RUBAMIN LIMITED
  • Publication number: 20080146819
    Abstract: Process for the preparation of (S)-(?)-?-ethyl-2-oxo-1-pyrrolidineacetamide of Formula (I) by the steps of condensation of (S)-2-amino butanol of Formula (II) and 4-halobutryl chloride, where halo group can be chloro, bromo or iodo in solvents to form ?-ethyl-2-oxo pyrrolidine ethanol of Formula (III); oxidation of (S)-?-ethyl-2-oxo pyrrolidine ethanol to yield (S)-?-ethyl-2-oxo pyrrolidine acetic acid having the formula (IV); esterification of (S)-?-ethyl-2-oxo pyrrolidine acetic acid (IV) with an alcohol to provide alkyl ester of Formula (V) wherein, R is 14 Carbon atom; ammonolysis of alkyl esters of formula (V) with ammonia to provide (S)-(?)—?-ethyl-2-oxo-1-pyrrolidine acetamide of formula (1).
    Type: Application
    Filed: January 20, 2006
    Publication date: June 19, 2008
    Applicant: RUBAMIN LIMITED
    Inventors: Arun Kanti Mandal, Satish Wasudeo Mahajan, Madan Kumar Sharma, Apurba Chetia, Nitesh Dolatram Chauhan