Patents Assigned to Ruhr-Universität Bochum
-
Patent number: 11866757Abstract: Methods using plasma-driven generation of H2O2 in an aqueous liquid may provide a substrate to enzymes, which are then capable to oxidize or hydroxylate organic compounds. A plasma device may produce an aqueous liquid comprising H2O2 for use in an enzymatic reaction.Type: GrantFiled: June 11, 2019Date of Patent: January 9, 2024Assignee: Ruhr-Universitaet BochumInventors: Julia Bandow, Abdulkadir Yayci, Marco Krewing, Robert Kourist, Alvaro Gomez Baraibar
-
Patent number: 11800627Abstract: A probe for measuring plasma parameters by means of active plasma resonance spectroscopy comprises an external coupling, a balun, an internal coupling, and a probe head. It is provided that the couplings, the balun, and the probe head are integrated in an electrically-insulating substrate cylinder, and the substrate cylinder has a layered structure made from multiple substrate layers along its rotational axis. In this way, a probe for measuring plasma parameters is provided which enables an improved measurement of the plasma parameters, wherein the plasma is influenced as little as possible during the measurement of the plasma parameters.Type: GrantFiled: June 25, 2019Date of Patent: October 24, 2023Assignee: RUHR-UNIVERSITÄT BOCHUMInventors: Dennis Pohle, Christian Schulz, Ilona Rolfes
-
Patent number: 11298337Abstract: The present invention relates to a compound reducing microtubule detyrosination in axonal tips selected from the group consisting of tubulin carboxypeptidase inhibitors and tubulin tyrosine ligase activators and combinations thereof for use in the treatment of axonal damage.Type: GrantFiled: August 29, 2019Date of Patent: April 12, 2022Assignee: RUHR-UNIVERSITÄT BOCHUMInventors: Philipp Ludwig Alexander Gobrecht, Dietmar Fischer
-
Patent number: 11267831Abstract: A complex having the structure of formula (I) is disclosed. L1, L2, L3, L4, and L5 may be or include independently metal-coordinating ligands selected from the group consisting of neutral ligands, anionic ligands, and mixed ligands, and combinations thereof. In a non-limiting embodiment, the complex is an N-heterocyclic carbene (NHC) Re(I) complex having an unsubstituted or substituted benzimidazol-2-ylidene ligand. The complex may be included in a pharmaceutical composition for treating gram (+) bacterial infections.Type: GrantFiled: June 18, 2018Date of Patent: March 8, 2022Assignee: Ruhr-Universitaet BochumInventors: Nils Metzler-Nolte, Daniel Siegmund, Julia Bandow, Sina Schaekermann
-
Patent number: 11179407Abstract: The present invention relates to L-arabino-oligosaccharides, in particular synthetically produced L-arabino-oligosaccharides and their uses for the prophylaxis of allergic reactions in mammals.Type: GrantFiled: November 30, 2016Date of Patent: November 23, 2021Assignees: FORSCHUNGSZENTRUM BORSTEL LEIBNIZ-ZENTRUM FÜR MEDIZIN UND BIOWISSENSHAFTEN, UNIVERSITÄT ROSTOCK, RUHR-UNIVERSITÄT BOCHUMInventors: Marcus Peters, Otto Holst, Christian Vogel, Alice Voss
-
Publication number: 20210039319Abstract: Beginning on a starting area on a surface of a digital model, a layered subdivision of the model takes place to produce a three-dimensional object. Positioning of the layers on the starting area is based on calculation of a distance field, which assigns to each point of the model volume a shortest distance within the volume to the nearest starting area. For each discrete point of a layer defined by a distance field an orientation of a processing head is determined. The surface normal of the layer is calculated or gradient vectors of the distance field are calculated, which show a direction of the steepest rise in distances for the discrete point. Shape and distribution of layers conform to the shape of the digital model. The sequence for the adaptive construction results from the assignment of the layers to distance values, beginning with a lowest distance value in ascending order.Type: ApplicationFiled: February 13, 2018Publication date: February 11, 2021Applicant: RUHR-UNIVERSITÄT BOCHUMInventors: Michael RIEGER, BENJAMIN JOHNEN, BERND KUHLENKÖTTER
-
Patent number: 10226763Abstract: The present invention relates to a process for preparing at least one sheet silicate comprising Ga and/or Zn, and based thereon, a framework silicate, preferably of the RRO structure type, to the sheet silicate and framework silicate themselves and to the uses of the silicates, especially of the framework silicate, preferably as catalysts.Type: GrantFiled: November 20, 2015Date of Patent: March 12, 2019Assignees: BASF SE, RUBITEC-GESELLSCHAFT FUER INNOVATION UND TECHNOLOGIE DER RUHR-UNIVERSITAET BOCHUM MBHInventors: Ulrich Mueller, Natalia Trukhan, Hermann Gies, Bart Tijsebaert, Csaba Varszegi, Dirk De Vos
-
Patent number: 9950017Abstract: The present invention relates to a pharmaceutical composition which includes naturally occurring, non-transgenic isolated bacteria from the group of Lactococcus and Acinetobacter or fragments thereof or mixtures thereof, to such a bacterium as a medicament for the prevention and/or treatment of allergic or chronic inflammatory disorders and to a process for producing this composition.Type: GrantFiled: March 3, 2008Date of Patent: April 24, 2018Assignees: FORSCHUNGSZENTRUM BORSTEL, RUHR-UNIVERSITÄT BOCHUMInventors: Albrecht Bufe, Otto Holst, Harald Renz, Erika Von Mutius, Johann Bauer, Nicole Blumer, Jennifer Debarry, Markus Ege, Susanne Friedrich, Holger Garn, Soren Gatermann, Anna Hanuszkiewicz, Holger Heine, Michael Wegmann
-
Publication number: 20160074851Abstract: The present invention relates to a process for preparing at least one sheet silicate comprising Ga and/or Zn, and based thereon, a framework silicate, preferably of the RRO structure type, to the sheet silicate and framework silicate themselves and to the uses of the silicates, especially of the framework silicate, preferably as catalysts.Type: ApplicationFiled: November 20, 2015Publication date: March 17, 2016Applicants: BASF SE, RUBITEC-GESELLSCHAFT FUER INNOVATION UND TECHNOLOGIE DER RUHR-UNIVERSITAET BOCHUM MBHInventors: Ulrich MUELLER, Natalia TRUKHAN, Hermann GIES, Bart TIJSEBAERT, Csaba VARSZEGI, Dirk DE VOS
-
Patent number: 9221692Abstract: The present invention relates to a process for preparing at least one sheet silicate comprising Ga and/or Zn, and based thereon, a framework silicate, preferably of the RRO structure type, to the sheet silicate and framework silicate themselves and to the uses of the silicates, especially of the framework silicate, preferably as catalysts.Type: GrantFiled: April 3, 2008Date of Patent: December 29, 2015Assignees: BASF SE, RUBITEC-GESELLSCHAFT FUER INNOVATION UND TECHNOLOGIE DER RUHR-UNIVERSITAET BOCHUM MBHInventors: Ulrich Mueller, Natalia Trukhan, Hermann Gies, Bart Tijsebaert, Csaba Varszegi, Dirk De Vos
-
Patent number: 9113543Abstract: The invention relates to a device and method for measuring the density of a plasma by determining an impulse response to a high-frequency signal coupled into a plasma. The density, electron temperature and/or collision frequency as a function of the impulse response can be determined. A probe having a probe head and a probe shaft can be introduced into the plasma, wherein the probe shaft is connected to a signal generator for electrically coupling a high-frequency signal into the probe head. The probe core is enclosed by the jacket and has at its surface mutually insulated electrode areas of opposite polarity. A balun is arranged at the transition between the probe head and an electrically unbalanced high-frequency signal feed to convert electrically unbalanced signals into balanced signals.Type: GrantFiled: October 6, 2011Date of Patent: August 18, 2015Assignee: RUHR-UNIVERSITÄT BOCHUMInventors: Ralf Peter Brinkmann, Jens Oberrath, Peter Awakowicz, Martin Lapke, Thomas Musch, Thomas Mussenbrock, Ilona Rolfes, Christian Schulz, Robert Storch, Tim Styrnoll, Christian Zietz
-
Patent number: 8933629Abstract: A method of establishing a DC bias in front of at least one electrode in a plasma operating apparatus by applying an RF voltage with at least two harmonic frequency components with a controlled relative phase between the components, where at least one of the higher frequency components is established as an even multiple of the lower frequency component.Type: GrantFiled: November 8, 2013Date of Patent: January 13, 2015Assignee: Ruhr-Universität BochumInventors: Brian George Heil, Uwe Czarnetzki, Ralf Peter Brinkmann, Thomas Mussenbrock
-
Patent number: 8892431Abstract: A smoothing method for suppressing fluctuating artifacts in the reduction of interference noise includes the following steps: providing short-term spectra for a sequence of signal frames, transforming each short-term spectrum by way of a forward transformation which describes the short-term spectrum using transformation coefficients that represent the short-term spectrum subdivided into its coarse and fine structures; smoothing the transformation coefficients with the respective same coefficient indices by combining at least two successive transformed short-term spectra; and transforming the smoothed transformation coefficients into smoothed short-term spectra by way of a backward transformation.Type: GrantFiled: June 25, 2008Date of Patent: November 18, 2014Assignees: Ruhr-Universitaet Bochum, Siemens AudiologischeTechnik GmbHInventors: Timo Gerkmann, Colin Breithaupt, Rainer Martin
-
Patent number: 8643280Abstract: A method of establishing a DC bias in front of at least one electrode in a plasma operating apparatus by applying an RF voltage with at least two harmonic frequency components with a controlled relative phase between the components, where at least one of the higher frequency components is established as an even multiple of the lower frequency component.Type: GrantFiled: July 11, 2008Date of Patent: February 4, 2014Assignee: Ruhr-Universität BochumInventors: Brian George Heil, Uwe Czarnetzki, Ralf Peter Brinkmann, Thomas Mussenbrock
-
Publication number: 20130160523Abstract: The invention relates to a device and method for measuring the density of a plasma by determining an impulse response to a high-frequency signal coupled into a plasma. The density, electron temperature and/or collision frequency as a function of the impulse response can be determined. A probe having a probe head and a probe shaft can be introduced into the plasma, wherein the probe shaft is connected to a signal generator for electrically coupling a high-frequency signal into the probe head. The probe core is enclosed by the jacket and has at its surface mutually insulated electrode areas of opposite polarity. A balun is arranged at the transition between the probe head and an electrically unbalanced high-frequency signal feed to convert electrically unbalanced signals into balanced signals.Type: ApplicationFiled: October 6, 2011Publication date: June 27, 2013Applicant: RUHR-UNIVERSITÄT BOCHUMInventors: Ralf Peter Brinkmann, Jens Oberrath, Peter Awakowicz, Martin Lapke, Thomas Musch, Thomas Mussenbrock, Ilona Rolfes, Christian Schulz, Robert Storch, Tim Styrnoll, Christian Zietz
-
Patent number: 8372963Abstract: The present invention relates to a nucleic acid molecule, which codes for the F-protein of the respiratory syncytial virus (RSV) or a fragment thereof, for the expression in a human cell environment of codon optimized variants of said nucleic acid molecule, vectors and compositions comprising said nucleic acid molecules and the use thereof as vaccines and polypeptides coded by the nucleic acid molecules and method for the production thereof.Type: GrantFiled: December 18, 2007Date of Patent: February 12, 2013Assignees: Pevion Biotech AG, Ruhr-Universitaet BochumInventors: Thomas Grunwald, Klaus Ueberla
-
Publication number: 20100182510Abstract: A smoothing method for suppressing fluctuating artifacts in the reduction of interference noise includes the following steps: providing short-term spectra for a sequence of signal frames, transforming each short-term spectrum by way of a forward transformation which describes the short-term spectrum using transformation coefficients that represent the short-term spectrum subdivided into its coarse and fine structures; smoothing the transformation coefficients with the respective same coefficient indices by combining at least two successive transformed short-term spectra; and transforming the smoothed transformation coefficients into smoothed short-term spectra by way of a backward transformation.Type: ApplicationFiled: June 25, 2008Publication date: July 22, 2010Applicants: RUHR-UNIVERSITÄT BOCHUM, SIEMENS AUDIOLOGISCHE TECHNIK GMBHInventors: Timo Gerkmann, Colin Breithaupt, Rainer Martin
-
Patent number: 6483288Abstract: An engagement detection circuit for a clock recovery circuit consisting of a phase detector (3), a counter element (6) and a flip-flop (8). By employing a low-pass element (12) and a trigger element (13) connected downstream, a preliminary and a final engagement of a phase control circuit can be detected with the engagement detection circuit. This provides a clock recovery circuit for controlling a phase control loop with a phase detector (20), a loop filter (21), a voltage-controlled oscillator (22) and a controllable frequency divider (23).Type: GrantFiled: November 2, 2000Date of Patent: November 19, 2002Assignee: Rubitec-Gesellschaft für Innovation und Technologie der Ruhr Universität Bochum mbHInventor: Johann Christoph Scheytt
-
Patent number: 6300198Abstract: In order to produce a vertical MOS transistor with optimized gate overlap capacitances, a mesa structure is formed with an upper source/drain region, a channel region and a lower source/drain region. With the aid of chemical/mechanical polishing, an insulation structure is formed which essentially covers the side walls of the lower source/drain region. A gate dielectric and a gate electrode, whose height is essentially equal to the height of the channel region, are formed on the side walls of the channel region.Type: GrantFiled: September 16, 1999Date of Patent: October 9, 2001Assignees: Siemens Aktiengesellschaft, Ruhr-Universität BochumInventors: Thomas Aeugle, Wolfgang Rösner, Dag Behammer