Patents Assigned to RUPRECHT-KARLS-UNIVERISTAET HEIDELBERG
  • Means and methods for treating or diagnosing IDH1 R132H mutant-positive cancers
    Patent number: 10161940
    Abstract: The present invention concerns the field of tumor therapeutics and diagnostics. Specifically, it relates to a peptide comprising at least 8 amino acids in length which are present as contiguous amino acid sequence in the human Isocitratdehydrogenase Type 1 (IDH1), wherein said peptide has at least one amino acid exchange from R to H at a position corresponding to position 132, for use in preventing and/or treating cancer. Further contemplated is a medicament comprising the said peptide.
    Type: Grant
    Filed: January 3, 2013
    Date of Patent: December 25, 2018
    Assignees: DEUTSCHES KREBSFORSCHUNGSZENTRUM, RUPRECHT-KARLS-UNIVERISTAET HEIDELBERG
    Inventors: Michael Platten, Theresa Bunse, Wolfgang Wick
  • Means and Methods for Diagnosing and Monitoring Heart Failure in a Subject
    Publication number: 20150160238
    Abstract: The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing heart failure in a subject and a method for monitoring progression or regression of heart failure in a subject. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Application
    Filed: July 27, 2012
    Publication date: June 11, 2015
    Applicants: RUPRECHT-KARLS-UNIVERISTÄT HEIDELBERG, METANOMICS GMBH
    Inventors: Regina Reszka, Jens Fuhrmann, Jürgen Kastler, Bianca Bethan, Martin Kluttig, Hugo A. Katus, Norbert Frey, Johanna Wolf, Tanja Weis