Patents Assigned to RUPRECHT-KARLS UNIVERSITY OF HEIDELBERG
  • ABHD5 and partial HDAC4 fragments and variants as a therapeutic approach for the treatment of cardiovascular diseases
    Patent number: 9914912
    Abstract: The present invention relates to Abhydrolase containing domain 5 (ABHD5) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHD5 for the identification of novel compounds which are useful for the treatment of heart failure.
    Type: Grant
    Filed: February 17, 2014
    Date of Patent: March 13, 2018
    Assignee: Ruprecht-Karls-University Heidelberg
    Inventors: Johannes Backs, Zegeye Jebessa, Lorenz Lehmann, Hugo Katus, Oliver Müller
  • MICRORNA FOR DIAGNOSIS OF PANCREATIC CANCER
    Publication number: 20130310276
    Abstract: The present invention relates to methods for improving the diagnosis of pancreatic and ampullary adenocarcinomas by making use of specific mi RNA biomarkers and/or mi RNA classifiers.
    Type: Application
    Filed: December 21, 2011
    Publication date: November 21, 2013
    Applicants: RUPRECHT-KARLS UNIVERSITY OF HEIDELBERG, HERLEV HOSPITAL
    Inventors: Julia Sidenius Johansen, Nicolai Aagaard Schultz, Jens Werner, Morten Wøjdemann