Abstract: Therapeutic compositions for the treatment of acne which comprise from about 0.1% to about 5% by weight naringin, from about 0.1% to about 10% by weight naringenin, from about 0.05% to about 5% by weight of an antimicrobially active partially hydrolyzed naringin, from about 0.01% to about 5% weight colloidal silica, and from about 80% to 97% by weight of a solvent.