Patents Assigned to RxKinetix, Inc.
  • Particulate drug-containing products and method of manufacture
    Patent number: 7125566
    Abstract: Provided is a compressed anti-solvent technique for manufacture of drug-containing powders for pulmonary delivery. The drug is processed in a cosolvent system including two or more mutually soluble organic solvents. Also provided are powders manufacturable by the manufacture method, including powders of substantially pure drug and powders including a biocompatible polymer for pulmonary sustained drug release applications. Also provided are packaged products including drug-containing powder in a container that is receivable by and operable with a dry powder inhaler to produce an aerosol including dispersed drug-containing particles when the inhaler is actuated.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: October 24, 2006
    Assignee: RxKinetix, Inc.
    Inventor: Jeffrey B. Etter
  • Composition for delivery of hematopoietic growth factor
    Patent number: 6875441
    Abstract: A hematopoietic growth factor delivery composition includes a hematopoietic growth factor, a liquid vehicle, a first biocompatible polymer and a second biocompatible polymer. The composition exhibits reverse-thermal viscosity behavior, due to interaction between the first biocompatible polymer and the liquid vehicle. The second biocompatible polymer helps to protect the first biocompatible polymer from being dissolved in vivo following administration to a host.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: April 5, 2005
    Assignee: RxKinetix, Inc.
    Inventors: Gary J. Rosenthal, Jeffrey B. Etter
  • Particulate insulin-containing products and method of manufacture
    Patent number: 6761909
    Abstract: Provided is a compressed anti-solvent technique for manufacture of insulin-containing powders for pulmonary delivery. The insulin is processed in a cosolvent system including two or more mutually soluble organic solvents. Also provided are powders manufacturable by the manufacture method, including powders of substantially pure insulin and powders including a biocompatible polymer for pulmonary sustained insulin release applications. Also provided are packaged products including insulin-containing powder in a container that is receivable by and operable with a dry powder inhaler to produce an aerosol including dispersed insulin-containing particles when the inhaler is actuated.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: July 13, 2004
    Assignee: RxKinetix, Inc.
    Inventor: Jeffrey B. Etter
  • Treatment of mucositis
    Patent number: 6685917
    Abstract: This present invention provides a therapeutic composition for use in the treatment of mucositis and a method for using such a therapeutic composition. The therapeutic composition includes a pharmaceutical substance effective for treating mucositis formulated with a biocompatible polymer, such as a biocompatible reverse-thermal gelation polymer.
    Type: Grant
    Filed: November 21, 2001
    Date of Patent: February 3, 2004
    Assignee: RxKinetix, Inc.
    Inventors: Gary J. Rosenthal, Jeffrey B. Etter, Timothy C. Rodell, Wren H. Schauer, Adrian Samaniego
  • Particulate drug-containing products and method of manufacture
    Patent number: 6669960
    Abstract: Provided is a compressed anti-solvent technique for manufacture of drug-containing powders for pulmonary delivery. The drug is processed in a cosolvent system including two or more mutually soluble organic solvents. Also provided are powders manufacturable by the manufacture method, including powders of substantially pure drug and powders including a biocompatible polymer for pulmonary sustained drug release applications. Also provided are packaged products including drug-containing powder in a container that is receivable by and operable with a dry powder inhaler to produce an aerosol including dispersed drug-containing particles when the inhaler is actuated.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: December 30, 2003
    Assignee: RxKinetix, Inc.
    Inventor: Jeffrey B. Etter
  • Methods for use of delivery composition for expanding, activating, committing or mobilizing one or more pluripotent, self-renewing and committed stem cells
    Patent number: 6649189
    Abstract: A hematopoietic growth factor delivery composition includes a hematopoietic growth factor, a liquid vehicle, a first biocompatible polymer and a second biocompatible polymer. The composition exhibits reverse-thermal viscosity behavior, due to interaction between the first biocompatible polymer and the liquid vehicle. The second biocompatible polymer helps to protect the first biocompatible polymer from being dissolved in vivo following administration to a host.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: November 18, 2003
    Assignee: RxKinetix, Inc.
    Inventors: James E. Talmadge, Gary J. Rosenthal, Jeffrey B. Etter