Patents Assigned to S.A. Nycomed Christiaens N.V.
  • Process for converting a xanthine ring or xanthine ring derivatives into dialkylaminoxanthine derivatives
    Patent number: 5739331
    Abstract: The invention relates to a process for the preparation of bamifylline or etamiphylline, in which a mixture comprising:a) theophylline or 8-benzyltheophyl-line;b) an alkyl dihalide; andc) a molar excess of an amineis reacted in the presence of a weak base, the reaction being carried out at a temperature higher than 90.degree. C. and under a pressure higher than 10.sup.5.
    Type: Grant
    Filed: September 29, 1995
    Date of Patent: April 14, 1998
    Assignee: S.A. Nycomed Christiaens N.V.
    Inventors: Fernand Thyrion, Hong Yang, Michel Parmantier