Abstract: This invention relates to novel tetrahydroazepinoindoles used in the preparation of novel alkyl pyrrolo(2,3-d)carbazole-6-carboxylates and to addition salts thereof; and to preparation of the same by a synthesis sequence starting from a tryptamine and a 3-halopyruvate and involving a rearrangement of the reaction mixture, said rearrangement being effected by heating the reaction mixture in the presence of a base. The pyrrolo(2,3-d)carbazole final products have both antianoxic and psychotropic activities.

Abstract: This invention relates to alkyl pyrrolo(2,3-d) carbazole-6-carboxylates having antianoxic, psychotropic and hemodynamic properties and to addition salts thereof; and to preparation of the same by a synthesis sequence starting from a tryptamine and a 3-halopyruvate and involving a rearrangement of an addition compound with an aldehyde, said rearrangement being effected by Nb-alkylation of the aforementioned addition compound; and to pharmaceutical compositions containing the same; and to tetrahydroazepinoindoles used in the preparation of the same.