Abstract: A digital apparatus for treating cancer cachexia in a subject are provided. A processor of the digital apparatus provides, by the digital apparatus to the subject, one or more first modules selected from the group consisting of external activity modules and an internal activity module, each of the one or more first modules comprising one or more first instructions for the subject to follow. The one or more first instructions are selected from a plurality of external activity instructions of the external activity modules and a plurality of internal activity instructions of the internal activity module. The processor provides the one or more first module for a predetermined period having a plurality of sections, each of the plurality of sections comprises different combinations of the plurality of external activity instructions of the external activity module.

Abstract: Systems and methods for improving an eyesight of a subject are provided. A system may include a digital apparatus, which may include a digital instruction generation unit configured to generate one or more digital therapeutic modules for improving the eyesight based on a mechanism of action (MOA) in and a therapeutic hypothesis for improving the eyesight, generate specified digital instructions based on the one or more digital therapeutic modules and provide the digital instructions to a first user, and an outcome collection unit configured to collect the first user's execution outcomes of the digital instructions. The system may also include a healthcare provider portal for a healthcare provider to manage their patients and/or an administrative portal.

Abstract: Methods and devices for mitigating emotional and physical tension or stress before, during or after a medical procedure. The present disclosure also provides methods for providing a series of visual and/or auditory inputs provided to a subject, wherein subsequent inputs are determined based on feedback from the subject following earlier inputs.

Abstract: Systems and methods for cancer cachexia therapy are provided. A system may include a digital apparatus, which may include a digital instruction generation unit configured to generate digital therapeutic modules for treating cancer cachexia, generate specified digital instructions based on the digital therapeutic modules and provide the digital instructions to a first user, and an outcome collection unit configured to collect the first user's execution outcomes of the digital instructions.

Abstract: Methods and apparatuses an described herein for treating a patient with mild cognitive impairment (MCI) or dementia by one or more digital therapeutics. The method comprises providing an electronic device to the patient, one or more first modules selected from the group consisting of a lifestyle change module, an execution environment module, a leaning/memory module, an exercise module, and an affirmative/accomplishment module, each of the one or more first modules comprising one or more first instructions for the patient to follow.

Abstract: Systems and methods for arthritis therapy are provided. A system may include a digital apparatus, which may include a digital instruction generation unit configured to generate digital therapeutic modules for preventing or ameliorating arthritis, generate specified digital instructions based on the digital therapeutic modules and provide the digital instructions to a first user, and an outcome collection unit configured to collect the first user's execution outcomes of the digital instructions.

Abstract: The present disclosure provides various methods and systems for strengthening or increasing mass of a pelvic floor muscle in a subject by providing, by an electronic device to the subject, one or more first modules selected from the group consisting of an exercise and/or life style module, a sitz bath module, a pelvic splanchnic nerve and/or pelvic muscle exercise module, and a vagal nerve system and/or gastrointestinal (GI) exercise module, each of the one or more first modules comprising one or more first instructions for the subject to follow.

Abstract: Systems and methods for treating social communication disorder are provided. A system may include a digital apparatus, which may include a digital instruction generation unit configured to generate instructions in real-time or near-real-time for the user to follow to treat social communication disorder based on a mechanism of action (MOA) in and a therapeutic hypothesis for the social communication disorder, and an outcome collection unit configured to collect the user's execution outcomes of the digital instructions. The system may also include a healthcare provider portal for a healthcare provider to manage their patients and/or an administrative portal for an administrator to manage healthcare providers.

Abstract: Methods and apparatuses are described herein for enhancing performance of a user. For example, an apparatus may generate one or more performance enhancing instructions that cause, based on the user's performance of the performance enhancing instructions, at least one physiological changes in the user's physiological mechanism to cope with at least one of anxiety or stress. The at least one physiological changes may include at least one of dopamine secretion induction, oxytocin secretion induction, cortisol level reduction, melatonin secretion induction, or synapsing promotion. The apparatus may then provide the user the one or more performance enhancing instructions via the apparatus. The one or more performance enhancing instructions may comprise a first/second concentration enhancing digital instruction, an anxiety/stress reducing digital instruction, and a coordination & agility enhancing digital instruction.

Abstract: A method for generating treatment regimen for one or more health conditions includes retrieving a stored healthcare treatment model that has been trained to identify, for each of a plurality of health conditions, one or more respective treatment programs. Each of the treatment programs includes a respective treatment user interface to modify a respective behavior associated with one or more neurohumoral factors that are associated with the respective health condition. In response to receiving input that specifies a first health condition of the one or more health conditions, the method uses the healthcare treatment model to select one or more treatment programs corresponding to the first health condition and provides the treatment user interfaces for the one or more treatment programs.

Abstract: Systems and methods for maintaining, optimizing, or strengthening an immune system of a subject are provided.

Abstract: Systems and methods for cancer cachexia therapy are provided. A system may include a digital apparatus, which may include a digital instruction generation unit configured to generate digital therapeutic modules for treating cancer cachexia, generate specified digital instructions based on the digital therapeutic modules and provide the digital instructions to a first user, and an outcome collection unit configured to collect the first user's execution outcomes of the digital instructions.

Abstract: Systems and methods for treating myopia are provided. A system may include a digital apparatus, which may include a digital instruction generation unit configured to generate digital therapeutic modules for treating myopia based on a mechanism of action (MOA) in and a therapeutic hypothesis for the myopia, generate specified digital instructions based on the digital therapeutic modules and provide the digital instructions to a first user, and an outcome collection unit configured to collect the first user's execution outcomes of the digital instructions. The system may also include a healthcare provider portal for a healthcare provider to manage their patients and/or an administrative portal.

Abstract: Systems and methods for treating myopia are provided. A system may include a digital apparatus, which may include a digital instruction generation unit configured to generate digital therapeutic modules for treating myopia based on a mechanism of action (MOA) in and a therapeutic hypothesis for the myopia, generate specified digital instructions based on the digital therapeutic modules and provide the digital instructions to a first user, and an outcome collection unit configured to collect the first user's execution outcomes of the digital instructions. The system may also include a healthcare provider portal for a healthcare provider to manage their patients and/or an administrative portal.

Abstract: Methods and apparatuses are described herein for treating a patient with mild cognitive impairment (MCI) or dementia by one or more digital therapeutics. For example, a patient who has been diagnosed with the MCI or dementia may administer one or more digital therapeutics to the patient to improve a plurality of neurohumoral factors that cause the MCI or the dementia of the patient. The digital therapeutics may include one or more digital instructions that are generated to treat at least one imbalance of the plurality of neurohumoral factors based on at least one neurohumoral change among the plurality of neurohumoral factors by the patient's performance of the one or more digital instructions. The one or more digital instructions may include at least one of an execution environment setting, a lifestyle change, learning, exercising, or affirmation/achievement task.