Abstract: The present invention relates to combination therapy of a pyruvoyl derivative and an anti-oxidant, which is characterized by significant increase of the activity of microglia, inhibition of brain tissue damage by the activation of inflammatory cytokines, improvement of motor skill and recovery effect of neuronal damage. Compared to single treatment with each, this present invention provides a continuous high neuroprotective effect even after 6 hours from the onset of damage.
Type:
Application
Filed:
October 3, 2008
Publication date:
August 26, 2010
Applicant:
S.H. PHARMA., LTD
Inventors:
Sung-Hwa Yoon, Ja-Kyeong Lee, Ho-Joon Park, Young-Gyun Shin, Hae-Un Lee, Seung-Woo Kim, Hyun-Ji Kim