Abstract: A device removing a biological and/or chemical entity (C) from extracorporeal blood (B) is disclosed. The device has a hollow capture chamber with an inlet for the entry of the extracorporeal blood (B) and an outlet for the outflow of the extracorporeal blood (B) and a capture element inside the capture chamber having a reactant surface placed in contact with the extracorporeal blood (B) and a plurality of binding agents (A) for the biological and/or chemical entity to be removed (C) such that the biological and/or chemical entity (C), upon exiting the capture chamber, is removed from the extracorporeal blood (B) as linked to the reactant surface.
Type:
Grant
Filed:
November 16, 2020
Date of Patent:
March 7, 2023
Assignees:
ISTITUTO SCIENTIFICO ROMAGNOLO PER LO STUDIO E LA CURA DEI TUMORI (I.R.S.T.) S.R.L
Inventors:
Michel Rigaud, Wainer Zoli, Francesco Fabbri, Giulia Gallerani, Pietro Fici
Abstract: A device for removing a biological and/or chemical entity (C) from extracorporeal blood (B) is disclosed. The device has a hollow capture chamber with an inlet for the entry of the extracorporeal blood (B) and an outlet for the outflow of the extracorporeal blood (B) and a capture element inside the capture chamber having a reactant surface placed in contact with the extracorporeal blood (B) and a plurality of binding agents (A) for the biological and/or chemical entity to be removed (C) such that the biological and/or chemical entity (C), upon exiting the capture chamber, is removed from the extracorporeal blood (B) as linked to the reactant surface.
Type:
Grant
Filed:
April 24, 2017
Date of Patent:
December 15, 2020
Assignee:
ISTITUTO SCIENTIFICO ROMAGNOLO PER LO STUDIO E LA CURA DEI TUMORI (I.R.S.T.) S.R.L.
Inventors:
Michel Rigaud, Wainer Zoli, Francesco Fabbri, Giulia Gallerani, Pietro Fici
Abstract: A pressure limiting valve (1), operationally arranged between a high pressure zone and low pressure zone (HP, LP) of a hydraulic circuit, comprises: a valve body (4) defining a passage (11) for a fluid; a closing member (8) having a stem (10) and a closing head (9) connected thereto and movably engaged with the valve body (4) so as to move along a longitudinal or axial direction (X) between positions (P1, P2) for closing and opening the passage (11), in an opening direction (OD) and closing direction (CD), respectively; a sleeve (12) which is joined to the stem (10); a spring (S1) arranged between the sleeve (12) and the valve body (4) so as to exert a force on the closing member (8) along said longitudinal or axial direction (X), in the closing direction (CD); said sleeve (12) is irreversibly locked to the stem (10) by means of a threadless mechanical connection, in a predefined longitudinal or axial position of the said stem (10), so that the spring (S1) exerts a force of predefined value on the closing mem
Abstract: A gripping device for conveying sheets in silk-screen printing machines. The gripping device comprises a box-like gripping bar having an outwardly and upwardly slanted rear wall provided with a longitudinally extending stepped edge at the upper side for resting a sheet; a plurality of tiltable plate-like gripping elements, forming a flat jaw, are disposed side by side and hinged to the side edge of the gripping bar which is opposite to the slanted wall. A corresponding number of lifting arms for tilting the gripping plates are secured to a drive shaft which extends into a tubular portion of the box-like gripping bar; the gripping bar is provided at both ends carriages and control levers to cause rotation of the lifting arms and tilting of the gripping plates, against the action of biasing springs during running on the printing machine. This solution provides a wide gripping surface for the sheets, reduces specific pressures, and a gripper with a simplified design.