Abstract: A polymeric hybrid material with photothermal properties is provided. The polymeric hybrid material containing polydopamine and particles of at least one of the polymers that are homogeneously dispersed and stable in a basic aqueous medium, where the surfaces of said polymer particles are coated with polydopamine, and the particles of polyurethane are in a sub-micron scale.

Abstract: The invention provides modified Natural Killer (NK) cells expressing an antigen-specific functional T cell receptor (TCR) complex. These NK cells are used for T cell receptor (TCR) gene therapy in order to circumvent any risk of mispairing of the TCR ? and ? chains and to provide Major Histocompatibility Complex (MHC)-restricted antigen-specific cytotoxicity to the NK cells. The invention additionally provides methods for producing the modified NK cells, therapeutic compositions including the modified NK cells, and methods for using the modified NK cells in therapy of cancer, viral infections, autoimmunity, and graft versus host disease (GvHD).

Abstract: Optimized 3-D graphene structures used to enhance thermal performance of the thermal systems such as vapor chambers are provided. The porosity of the wick/porous structure has a critical effect on the efficiency of a vapor chamber system. Graphene coating provides high thermal conductivity, and it has a high porous structure, which is favorable for vapor chamber devices.

Abstract: A method for generating a tool path to manufacture a part using a computer numerical control system includes the steps of; generating an initial design part geometry from a geometry modelling program as an input, creating a pre-finished in-process workpiece geometry before a finishing process, controlling a stock thickness distribution of the pre-finished in-process workpiece geometry by following the tool path, wherein the stock thickness distribution is based on at least one ruling function on a basis of at least one predetermined direction, wherein the at least one ruling function is used to determine a stock thickness at a tool location to obtain a variable stock thickness distribution around a design part; locating at least one tool to be defined with respect to the initial design part geometry.

Abstract: A production method of boron carbide nano-sized particles and/or submicron particles includes the following sequential steps: obtention of a fluid mixture including elemental boron, glycerin and one or more carboxylic acid, wherein a molar ratio of glycerin to the one or more carboxylic acids is within a range between 10:1 and 10:7.5. Heating of the fluid mixture to obtain a first mid-product in a form of a gel including borate ester bonds. Solidification of the first mid-product by heating a reaction product to obtain a second mid-product in solid form. Sintering the second mid-product to obtain boron carbide in a form of particles.

Abstract: Pol ? protein inhibitor compounds are useful for selectively inhibiting the growth of MLH1 mutant/deficient tumor or cancer cells due to a synthetic lethal relationship between MLH1 and Pol ?. The compounds were shown to directly interact with Pol ? and inhibit its biological function and cause cancer cell death and an inhibition of tumor or cancer cell growth in multiple assays.

Abstract: A polyoxazoline-based electrolyte and a network formed by crosslinking of the electrolyte through its secondary amine groups with an epoxy resin are provided. The network is designed as a multifunctional energy storage system that is capable of transferring mobile lithium cations through the passageways present in its structure. The present invention also relates to a method that is used to obtain such a network and electrolyte.

Abstract: The invention provides modified Natural Killer (NK) cells expressing an antigen-specific functional T cell receptor (TCR) complex. These NK cells are used for T cell receptor (TCR) gene therapy in order to circumvent any risk of mispairing of the TCR a and ? chains and to provide Major Histocompatibility Complex (MHC)-restricted antigen-specific cytotoxicity to the NK cells. The invention additionally provides methods for producing the modified NK cells, therapeutic compositions including the modified NK cells, and methods for using the modified NK cells in therapy of cancer, viral infections, autoimmunity, and graft versus host disease (GvHD).

Abstract: A polymeric composition containing at least one polymer and halloysite nanotubes is disclosed. At least a portion of the halloysite nanotubes is loaded with a phase change material and each of the loaded halloysite nanotubes contains at most one kind of phase change material. In addition, a preparation method and use of the polymeric composition are further provided.

Abstract: A photothermal composition configured to be used in air filter for destroying bioaerosol particles by converting light energy emitted from a light source into heat energy including a photothermal agent is provided. The present invention also concerns an air filter for collecting the bioaerosol particles in an air flow and destroying said bioaerosol particles deposited thereon, including a photothermal agent which converts light energy emitted from a light source into heat energy.

Abstract: A system and method for improving reading ability simultaneously utilizing a distinctive protocol of multi-sensory learning and EEG biofeedback. The present invention more particularly relates to an EEG biofeedback system comprising a biofeedback apparatus in the form of a head-mountable device including an electrode array for measuring bioelectrical signals generated by a cerebral cortex of a user's brain and a computer device receiving and analyzing data collected by said biofeedback apparatus and providing audiovisual feedback to the user.

Abstract: A polymer matrix based superabsorbent material is provided, which is made of a polymer including nanoparticles with a particle size in the range of 0.1-500 nanometers, one or more water-soluble monomers suitable for radical polymerization, and at least one vinyl alkoxysilane derivative agent as a crosslinker. A method of producing the polymer matrix based superabsorbent material is also provided, which includes steps of: obtaining a solution by adding a solvent to the one or more water-soluble monomers suitable for the radical polymerization, obtaining a reaction mixture by adding the at least one vinyl alkoxysilane derivative agent as the crosslinker to the solution, adding the nanoparticles with the particle size in the range of 0.1-500 nanometers to the reaction mixture, and obtaining the polymer by a polymerization process.

Abstract: A high stability formulation in the form of an aqueous mixture is disclosed. The formulation containing a quaternary ammonium organosilane hydrolysate includes the structure A(CH3)2N+(CH2)3Si(OZ)3-n(OH)n, wherein “A” is a saturated or unsaturated aliphatic chain having 12 to 18 carbons, “n” is an integer ranging from 0 to 2, “Z” is methyl or ethyl. A method to obtain the formulation includes a first reaction in which the tertiary amine group having the structure A(CH3)2N is quaternized by alkylation with a reactant having the structure (CH2)3Si(OR)3X, wherein X is halogen.

Abstract: Provided are a novel immuno-optomagnetic point-of-care (PoC) assay and in particular, a method for detecting an analyte using magnetic nanoparticles and quantum dots (QD) having antibodies which are interfaced with the fabricated PoC biochip platform for quantitative analysis, and an immuno-optomagnetic detection method. The method also relates to methods of making such a plurality of conjugated magnetic quantum dot nanoparticles, methods of detecting analytes using such a plurality of conjugated quantum dot nanoparticles.

Abstract: Provided are a novel immuno-optomagnetic point-of-care (PoC) assay and in particular, a method for detecting an analyte using magnetic nanoparticles and quantum dots (QD) having antibodies which are interfaced with the fabricated PoC biochip platform for quantitative analysis, and an immuno-optomagnetic detection method. The method also relates to methods of making such a plurality of conjugated magnetic quantum dot nanoparticles, methods of detecting analytes using such a plurality of conjugated quantum dot nanoparticles.

Abstract: A device including a liquid's flow path having an upstream side and a downstream side, a plurality of flow restrictive elements providing material communication between the upstream side to the downstream side, a thermoelectric generator or a thermophotovoltaic cell in thermal connection with a portion of the device located at the downstream side with respect to the plurality of flow restrictive elements. The portion is provided with roughness elements for, in use, contacting a fluid flowing through the device and facilitating collapse of cavitation bubbles.

Abstract: A force-feedback brake pedal system for cooperative braking of an electric or hybrid vehicle having jointly a regenerative braking system and a frictional braking system includes a brake pedal which is pivotally mounted around a shaft or a bearing, an electronic circuitry which is in electrical communication with the regenerative braking system and the frictional braking system of the vehicle, an actuator for providing force feedback in accordance with the regenerative breaking and friction breaking of the vehicle, the actuator is in mechanical communication with the brake pedal. The force-feedback brake pedal system further includes a compliant element arranged between the brake pedal and the actuator, and a position sensor which, during operation, measuring the deflections of the compliant element and transmitting data to the electronic circuitry.

Abstract: A heat exchanger having a heat transfer surface provided with hyperthermophilic bacteria. The hyperthermophilic bacteria can be from the genera Archaea. The hyperthermophilic bacteria can further be from the genus Sulfolobus, and the hyperthermophilic bacteria can further be from the species Sulfolobus solfataricus. The heat exchanger can be adapted to pool-boiling heat transfer.

Abstract: An overspeed emergency brake system includes an overspeed detector magnet generating a brake actuation force and a kinematic constraint element guiding the movement of the magnet. The magnet and a kinematic constraint element in the brake system are arranged such that a linear brake actuation force is generated at a normal operating speed condition (i.e in a first position of the magnet with respect to the kinematic constraint element), due to the movement of the kinematic constraint element when guiding the magnet along a reaction surface and the kinematic constraint element converts the linear speed-force relationship into a nonlinear speed-force relationship in an overspeed condition (i.e a second position), while the magnet translates with respect to the kinematic constraint element generating a sharply increasing force for triggering the overspeed emergency brake.

Abstract: A method for generating a tool path to manufacture a part using a computer numerical control system includes the steps of; generating an initial design part geometry from a geometry modelling program as an input, creating a pre-finished in-process workpiece geometry before a finishing process, controlling a stock thickness distribution of the pre-finished in-process workpiece geometry by following the tool path, wherein the stock thickness distribution is based on at least one ruling function on a basis of at least one predetermined direction, wherein the at least one ruling function is used to determine a stock thickness at a tool location to obtain a variable stock thickness distribution around a design part; locating at least one tool to be defined with respect to the initial design part geometry.