Patents Assigned to Sadra Medical, Inc.
  • Publication number: 20150245909
    Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve.
    Type: Application
    Filed: March 26, 2015
    Publication date: September 3, 2015
    Applicant: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Dwight P. Morejohn, Kenneth J. Michlitsch
  • Publication number: 20150223933
    Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an anchor having an expandable braid. In some embodiments, the expandable braid is fabricated from a single strand of wire. In some embodiments, the expandable braid comprises at least one turn feature. The anchor and the valve preferably are configured for endovascular delivery and deployment.
    Type: Application
    Filed: April 21, 2015
    Publication date: August 13, 2015
    Applicant: SADRA MEDICAL, INC.
    Inventors: Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Amr Salahieh, Dwight P. Morejohn
  • Publication number: 20150127094
    Abstract: The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.
    Type: Application
    Filed: November 25, 2014
    Publication date: May 7, 2015
    Applicant: SADRA MEDICAL, INC.
    Inventors: Amr Salahieh, Hans F. Valencia, Brian D. Brandt, Claudio Argento, Ulrich R. Haug, Jean-Pierre Dueri, Daniel K. Hildebrand, Dwight P. Morejohn, Tom Saul
  • Patent number: 9011521
    Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an anchor having an expandable braid. In some embodiments, the expandable braid is fabricated from a single strand of wire. In some embodiments, the expandable braid comprises at least one turn feature. The anchor and the valve preferably are configured for endovascular delivery and deployment.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: April 21, 2015
    Assignee: Sadra Medical, Inc.
    Inventors: Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Amr Salahieh, Dwight P. Morejohn
  • Patent number: 9005273
    Abstract: Methods and devices for assessing the operation of a replacement heart valve. The method includes endovascularly delivering a replacement heart valve to a vicinity of a heart valve in an unexpanded configuration, and assessing the operation of the replacement heart valve in the vicinity of the heart valve before fully expanding the replacement heart valve. Methods and devices for assessing the location of a replacement heart valve. The method includes endovascularly delivering a replacement heart valve to a vicinity of the heart valve in an unexpanded configuration, expanding the replacement heart valve to a partially deployed configuration, and assessing the location of the replacement heart valve in the vicinity of the heart valve before fully expanding the replacement heart valve.
    Type: Grant
    Filed: April 4, 2007
    Date of Patent: April 14, 2015
    Assignee: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff Krolik
  • Patent number: 8992608
    Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: March 31, 2015
    Assignee: Sadra Medical, Inc.
    Inventors: Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Amr Salahieh, Dwight P. Morejohn, Kenneth J. Michlitsch
  • Publication number: 20150073541
    Abstract: A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.
    Type: Application
    Filed: September 18, 2014
    Publication date: March 12, 2015
    Applicant: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
  • Publication number: 20150073540
    Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
    Type: Application
    Filed: September 24, 2014
    Publication date: March 12, 2015
    Applicant: SADRA MEDICAL, INC.
    Inventors: Amr Salahieh, Jean-Pierre Dueri, Hans F. Valencia, Daniel K. Hildebrand, Brian D. Brandt, Dwight P. Morejohn, Claudio Argento, Tom Saul, Ulrich R. Haug
  • Patent number: 8951299
    Abstract: Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: February 10, 2015
    Assignee: Sadra Medical, Inc.
    Inventors: David Paul, Benjamin Sutton, Brian McCollum, Brian D. Brandt, Emma Leung, Kenneth M. Martin, Amr Salahieh, Daniel Hildebrand
  • Publication number: 20150012085
    Abstract: A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.
    Type: Application
    Filed: September 23, 2014
    Publication date: January 8, 2015
    Applicant: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
  • Patent number: 8894703
    Abstract: The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: November 25, 2014
    Assignee: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Hans F. Valencia, Brian D. Brandt, Claudio Argento, Ulrich R. Haug, Jean-Pierre Dueri, Daniel Hildebrand, Dwight P. Morejohn, Tom Saul
  • Patent number: 8858620
    Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: October 14, 2014
    Assignee: Sadra Medical Inc.
    Inventors: Amr Salahieh, Jean-Pierre Dueri, Hans F. Valencia, Daniel Hildebrand, Brian D. Brandt, Dwight P. Morejohn, Claudio Argento, Tom Saul, Ulrich R. Haug
  • Patent number: 8840662
    Abstract: A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: September 23, 2014
    Assignee: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff Krolik
  • Patent number: 8840663
    Abstract: A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: September 23, 2014
    Assignee: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff Krolik
  • Patent number: 8828078
    Abstract: A method for endovascularly replacing a patient's heart valve including the following steps: endovascularly delivering an anchor and a replacement valve supported within the anchor to a vicinity of the heart valve in a collapsed delivery configuration, the anchor having grasping elements adapted to grasp tissue in a vicinity of the heart valve; expanding the anchor, thereby rotating the grasping elements; and grasping the tissue with the rotating grasping elements.
    Type: Grant
    Filed: September 20, 2005
    Date of Patent: September 9, 2014
    Assignee: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Daniel Hildebrand, Tom Saul
  • Publication number: 20140243967
    Abstract: The present invention provides an apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes an expandable anchor supporting a replacement valve, the anchor and replacement valve being adapted for percutaneous delivery and deployment to replace the patient's heart valve, the anchor having a braid having atraumatic grasping elements adapted to grasp tissue in a vicinity of the patient's heart valve.
    Type: Application
    Filed: May 1, 2014
    Publication date: August 28, 2014
    Applicant: SADRA MEDICAL, INC.
    Inventors: Amr Salahieh, Daniel K. Hildebrand, Tom Saul
  • Publication number: 20140135912
    Abstract: The present invention relates to apparatus and methods for performing valvuloplasty. In some embodiments, the apparatus includes an expandable braid valvuloplasty device. In some embodiments, the methods and apparatus may be used as an adjunct to percutaneous heart valve replacement. In some embodiments, the apparatus and methods may provide a medical practitioner with feedback, monitoring or measurement information, e.g., information relevant to percutaneous transcatheter heart valve replacement.
    Type: Application
    Filed: November 11, 2013
    Publication date: May 15, 2014
    Applicant: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Dwight P. Morejohn, Daniel K. Hildebrand, Tom Saul
  • Publication number: 20140121766
    Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.
    Type: Application
    Filed: January 6, 2014
    Publication date: May 1, 2014
    Applicant: SADRA MEDICAL INC.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider
  • Publication number: 20140114405
    Abstract: Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.
    Type: Application
    Filed: December 31, 2013
    Publication date: April 24, 2014
    Applicant: SADRA MEDICAL, INC.
    Inventors: David J. Paul, Benjamin T. Sutton, Brian K. McCollum, Brian D. Brandt, Emma Leung, Kenneth M. Martin, Amr Salahieh, Daniel K. Hildebrand
  • Publication number: 20140114406
    Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.
    Type: Application
    Filed: December 31, 2013
    Publication date: April 24, 2014
    Applicant: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik