Patents Assigned to Sadra Medical, Inc.
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Publication number: 20150245909Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve.Type: ApplicationFiled: March 26, 2015Publication date: September 3, 2015Applicant: Sadra Medical, Inc.Inventors: Amr Salahieh, Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Dwight P. Morejohn, Kenneth J. Michlitsch
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Publication number: 20150223933Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an anchor having an expandable braid. In some embodiments, the expandable braid is fabricated from a single strand of wire. In some embodiments, the expandable braid comprises at least one turn feature. The anchor and the valve preferably are configured for endovascular delivery and deployment.Type: ApplicationFiled: April 21, 2015Publication date: August 13, 2015Applicant: SADRA MEDICAL, INC.Inventors: Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Amr Salahieh, Dwight P. Morejohn
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Publication number: 20150127094Abstract: The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.Type: ApplicationFiled: November 25, 2014Publication date: May 7, 2015Applicant: SADRA MEDICAL, INC.Inventors: Amr Salahieh, Hans F. Valencia, Brian D. Brandt, Claudio Argento, Ulrich R. Haug, Jean-Pierre Dueri, Daniel K. Hildebrand, Dwight P. Morejohn, Tom Saul
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Patent number: 9011521Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an anchor having an expandable braid. In some embodiments, the expandable braid is fabricated from a single strand of wire. In some embodiments, the expandable braid comprises at least one turn feature. The anchor and the valve preferably are configured for endovascular delivery and deployment.Type: GrantFiled: December 13, 2011Date of Patent: April 21, 2015Assignee: Sadra Medical, Inc.Inventors: Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Amr Salahieh, Dwight P. Morejohn
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Patent number: 9005273Abstract: Methods and devices for assessing the operation of a replacement heart valve. The method includes endovascularly delivering a replacement heart valve to a vicinity of a heart valve in an unexpanded configuration, and assessing the operation of the replacement heart valve in the vicinity of the heart valve before fully expanding the replacement heart valve. Methods and devices for assessing the location of a replacement heart valve. The method includes endovascularly delivering a replacement heart valve to a vicinity of the heart valve in an unexpanded configuration, expanding the replacement heart valve to a partially deployed configuration, and assessing the location of the replacement heart valve in the vicinity of the heart valve before fully expanding the replacement heart valve.Type: GrantFiled: April 4, 2007Date of Patent: April 14, 2015Assignee: Sadra Medical, Inc.Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff Krolik
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Patent number: 8992608Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve.Type: GrantFiled: June 26, 2009Date of Patent: March 31, 2015Assignee: Sadra Medical, Inc.Inventors: Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Amr Salahieh, Dwight P. Morejohn, Kenneth J. Michlitsch
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Publication number: 20150073541Abstract: A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.Type: ApplicationFiled: September 18, 2014Publication date: March 12, 2015Applicant: Sadra Medical, Inc.Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
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Publication number: 20150073540Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.Type: ApplicationFiled: September 24, 2014Publication date: March 12, 2015Applicant: SADRA MEDICAL, INC.Inventors: Amr Salahieh, Jean-Pierre Dueri, Hans F. Valencia, Daniel K. Hildebrand, Brian D. Brandt, Dwight P. Morejohn, Claudio Argento, Tom Saul, Ulrich R. Haug
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Patent number: 8951299Abstract: Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.Type: GrantFiled: October 13, 2009Date of Patent: February 10, 2015Assignee: Sadra Medical, Inc.Inventors: David Paul, Benjamin Sutton, Brian McCollum, Brian D. Brandt, Emma Leung, Kenneth M. Martin, Amr Salahieh, Daniel Hildebrand
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Publication number: 20150012085Abstract: A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.Type: ApplicationFiled: September 23, 2014Publication date: January 8, 2015Applicant: Sadra Medical, Inc.Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
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Patent number: 8894703Abstract: The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.Type: GrantFiled: June 22, 2011Date of Patent: November 25, 2014Assignee: Sadra Medical, Inc.Inventors: Amr Salahieh, Hans F. Valencia, Brian D. Brandt, Claudio Argento, Ulrich R. Haug, Jean-Pierre Dueri, Daniel Hildebrand, Dwight P. Morejohn, Tom Saul
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Patent number: 8858620Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.Type: GrantFiled: June 10, 2011Date of Patent: October 14, 2014Assignee: Sadra Medical Inc.Inventors: Amr Salahieh, Jean-Pierre Dueri, Hans F. Valencia, Daniel Hildebrand, Brian D. Brandt, Dwight P. Morejohn, Claudio Argento, Tom Saul, Ulrich R. Haug
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Patent number: 8840663Abstract: A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.Type: GrantFiled: December 23, 2003Date of Patent: September 23, 2014Assignee: Sadra Medical, Inc.Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff Krolik
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Patent number: 8840662Abstract: A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.Type: GrantFiled: October 27, 2011Date of Patent: September 23, 2014Assignee: Sadra Medical, Inc.Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff Krolik
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Patent number: 8828078Abstract: A method for endovascularly replacing a patient's heart valve including the following steps: endovascularly delivering an anchor and a replacement valve supported within the anchor to a vicinity of the heart valve in a collapsed delivery configuration, the anchor having grasping elements adapted to grasp tissue in a vicinity of the heart valve; expanding the anchor, thereby rotating the grasping elements; and grasping the tissue with the rotating grasping elements.Type: GrantFiled: September 20, 2005Date of Patent: September 9, 2014Assignee: Sadra Medical, Inc.Inventors: Amr Salahieh, Daniel Hildebrand, Tom Saul
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Publication number: 20140243967Abstract: The present invention provides an apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes an expandable anchor supporting a replacement valve, the anchor and replacement valve being adapted for percutaneous delivery and deployment to replace the patient's heart valve, the anchor having a braid having atraumatic grasping elements adapted to grasp tissue in a vicinity of the patient's heart valve.Type: ApplicationFiled: May 1, 2014Publication date: August 28, 2014Applicant: SADRA MEDICAL, INC.Inventors: Amr Salahieh, Daniel K. Hildebrand, Tom Saul
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Publication number: 20140135912Abstract: The present invention relates to apparatus and methods for performing valvuloplasty. In some embodiments, the apparatus includes an expandable braid valvuloplasty device. In some embodiments, the methods and apparatus may be used as an adjunct to percutaneous heart valve replacement. In some embodiments, the apparatus and methods may provide a medical practitioner with feedback, monitoring or measurement information, e.g., information relevant to percutaneous transcatheter heart valve replacement.Type: ApplicationFiled: November 11, 2013Publication date: May 15, 2014Applicant: Sadra Medical, Inc.Inventors: Amr Salahieh, Dwight P. Morejohn, Daniel K. Hildebrand, Tom Saul
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Publication number: 20140121766Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.Type: ApplicationFiled: January 6, 2014Publication date: May 1, 2014Applicant: SADRA MEDICAL INC.Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider
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Publication number: 20140114405Abstract: Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.Type: ApplicationFiled: December 31, 2013Publication date: April 24, 2014Applicant: SADRA MEDICAL, INC.Inventors: David J. Paul, Benjamin T. Sutton, Brian K. McCollum, Brian D. Brandt, Emma Leung, Kenneth M. Martin, Amr Salahieh, Daniel K. Hildebrand
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Publication number: 20140114406Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.Type: ApplicationFiled: December 31, 2013Publication date: April 24, 2014Applicant: Sadra Medical, Inc.Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik