Patents Assigned to Sadra Medical
-
Patent number: 7780725Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve.Type: GrantFiled: June 16, 2004Date of Patent: August 24, 2010Assignee: Sadra Medical, Inc.Inventors: Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Amr Salahieh, Dwight P. Morejohn, Kenneth J. Michlitsch
-
Patent number: 7748389Abstract: The present invention relates to apparatus for methods for endovascularly replacing a patient's heart valve. The apparatus includes an expandable anchor with leaflet engagement elements on the proximal end of the anchor and a replacement valve. The leaflet engagement elements can be used to prevent distal migration and insure proper positioning of the apparatus.Type: GrantFiled: October 21, 2004Date of Patent: July 6, 2010Assignee: Sadra Medical, Inc.Inventors: Amr Salahieh, Brian D. Brandt, Robert A. Gleshlider, Dwight P. Morejohn, Tom Saul
-
Patent number: 7712606Abstract: The invention provides a two-part package and method of use for a pre-attached medical implant and delivery tool system. The package includes a wet compartment and a dry compartment and allows a pre-attached implant and delivery tool system to be at least partially stored immersed in a fluid in the wet compartment and at least partially stored in the dry compartment. In one embodiment the implant comprises a replacement heart valve, and the heart valve is stored inside the wet compartment while the heart valve delivery tool remains dry in the dry compartment.Type: GrantFiled: February 2, 2006Date of Patent: May 11, 2010Assignee: Sadra Medical, Inc.Inventors: Amr Salahieh, Tom Saul, Robert Geshlider, Andrea Johnson, Dwight Morejohn, Daniel Hildebrand, Jean-Pierre Dueri
-
Patent number: 7445631Abstract: The present invention relates to an apparatus for replacing a native aortic valve, the apparatus includes an expandable anchor adapted to be endovascularly delivered and secured at a site within the native aortic valve. The expandable anchor has a delivery length in a delivery configuration substantially greater than a deployed length in a deployed configuration. The apparatus may also include and a replacement valve configured to be secured within the anchor.Type: GrantFiled: July 15, 2004Date of Patent: November 4, 2008Assignee: Sadra Medical, Inc.Inventors: Amr Salahieh, Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Dwight P. Morejohn
-
Publication number: 20080234814Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.Type: ApplicationFiled: June 3, 2008Publication date: September 25, 2008Applicant: Sadra Medical, Inc.Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff Krolik
-
Patent number: 7381219Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.Type: GrantFiled: December 23, 2003Date of Patent: June 3, 2008Assignee: Sadra Medical, Inc.Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff Krolik
-
Publication number: 20080125859Abstract: Methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an anchor to a vicinity of the heart valve, the anchor having a braid, and expanding the braid to a deployed configuration against the patient's tissue. The braid may be fabricated from a single strand of wire and/or may comprise at least one turn feature.Type: ApplicationFiled: February 8, 2008Publication date: May 29, 2008Applicant: Sadra Medical, Inc.Inventors: Amr Salahieh, Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Dwight P. Morejohn
-
Patent number: 7329279Abstract: Methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an anchor to a vicinity of the heart valve, the anchor having a braid, and expanding the braid to a deployed configuration against the patient's tissue. The braid may be fabricated from a single strand of wire and/or may comprise at least one the feature.Type: GrantFiled: July 15, 2004Date of Patent: February 12, 2008Assignee: Sadra Medical, Inc.Inventors: Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Amr Salahieh, Dwight P. Morejohn
-
Publication number: 20070162107Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an anchor having an expandable braid. In some embodiments, the expandable braid is fabricated from a single strand of wire. In some embodiments, the expandable braid comprises at least one turn feature. The anchor and the valve preferably are configured for endovascular delivery and deployment.Type: ApplicationFiled: March 9, 2007Publication date: July 12, 2007Applicant: Sadra Medical, Inc.Inventors: Ulrich Haug, Hans Valencia, Robert Geshlider, Tom Saul, Amr Salahieh, Dwight Morejohn
-
Publication number: 20050143809Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.Type: ApplicationFiled: November 5, 2004Publication date: June 30, 2005Applicant: Sadra Medical a Delaware CorporationInventors: Amr Salahieh, Jean-Pierre Dueri, Hans Valencia, Daniel Hildebrant, Brian Brandt, Dwight Morejohn, Claudio Argento, Tom Saul, Ulrich Haug
-
Publication number: 20050137689Abstract: A method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a catheter to a vicinity of the heart valve; deploying the anchor from the catheter; expanding the anchor to contact tissue at an anchor site; and retrieving the anchor into the catheter. The invention also includes an apparatus for endovascularly replacing a heart valve, including: a catheter; a replacement valve configured to be disposed within the catheter for delivery to a vicinity of the heart valve; and an expandable anchor configured to be disposed within the catheter for delivery to a vicinity of the heart valve, to be deployed from the catheter, to be expanded to contact tissue at an anchor site and to be retrieved back into the catheter after having been expanded.Type: ApplicationFiled: December 23, 2003Publication date: June 23, 2005Applicant: Sadra Medical, a Delware CorporationInventors: Amr Salahieh, Brian Brandt, Dwight Morejohn, Ulrich Haug, Jean-Pierre Dueri, Hans Valencia, Robert Geshlider, Jeff Krolik
-
Publication number: 20050137695Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.Type: ApplicationFiled: August 3, 2004Publication date: June 23, 2005Applicant: Sadra MedicalInventors: Amr Salahieh, Brian Brandt, Dwight Morejohn, Ulrich Haug, Jean-Pierre Dueri, Hans Valencia, Robert Geshlider
-
Publication number: 20050137688Abstract: A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.Type: ApplicationFiled: December 23, 2003Publication date: June 23, 2005Applicant: Sadra Medical, a Delaware CorporationInventors: Amr Salahieh, Brian Brandt, Dwight Morejohn, Ulrich Haug, Jean-Pierre Dueri, Hans Valencia, Robert Geshlider, Jeff Krolik
-
Publication number: 20050137690Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.Type: ApplicationFiled: December 23, 2003Publication date: June 23, 2005Applicant: Sadra MedicalInventors: Amr Salahieh, Brian Brandt, Dwight Morejohn, Ulrich Haug, Jean-Pierre Dueri, Hans Valencia, Robert Geshlider, Jeff Krolik
-
Publication number: 20050137699Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a sheath to a vicinity of the heart valve; deploying the anchor from the sheath; expanding the anchor with a deployment tool comprising a plurality of actuation elements to contact tissue at an anchor site; and retrieving the anchor into the sheath.Type: ApplicationFiled: November 5, 2004Publication date: June 23, 2005Applicant: Sadra Medical, a Delaware CorporationInventors: Amr Salahieh, Hans Valencia, Brian Brandt, Claudio Argento, Ulrich Haug, Jean-Pierre Dueri, Daniel Hildebrand, Dwight Morejohn, Tom Saul
-
Publication number: 20050137701Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.Type: ApplicationFiled: December 23, 2003Publication date: June 23, 2005Applicant: Sadra MedicalInventors: Amr Salahieh, Brian Brandt, Dwight Morejohn, Ulrich Haug, Jean-Pierre Dueri, Hans Valencia, Robert Geshlider
-
Publication number: 20050137696Abstract: Apparatus for protecting a patient against embolization during endovascular replacement of the patient's heart valve is provided, the apparatus including a replacement valve configured for endovascular delivery and deployment, and an embolic filter configured for disposal downstream of the replacement valve during deployment of the valve. Apparatus including a delivery catheter having an expandable replacement valve disposed therein, and an embolic filter advanceable along the delivery catheter for diverting emboli released during endovascular deployment of the replacement valve is also provided. Furthermore, methods for protecting a patient against embolization during endovascular replacement of the patient's heart valve are provided, the methods including the steps of endovascularly delivering a replacement valve to a vicinity of the patient's heart valve, endovascularly deploying an embolic filter downstream of the heart valve, and endovascularly deploying the replacement valve.Type: ApplicationFiled: August 17, 2004Publication date: June 23, 2005Applicant: Sadra MedicalInventors: Amr Salahieh, Brian Brandt, Dwight Morejohn, Kenneth Michlitsch, Tom Saul
-
Publication number: 20050137686Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulic or non-pneumatic actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor.Type: ApplicationFiled: December 23, 2003Publication date: June 23, 2005Applicant: Sadra Medical, a Delaware CorporationInventors: Amr Salahieh, Brian Brandt, Dwight Morejohn, Ulrich Haug, Jean-Pierre Dueri, Hans Valencia, Robert Geshlider, Jeff Krolik
-
Publication number: 20050137691Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a custom-designed anchor; and a replacement valve, wherein the custom-designed anchor is adapted to engage native leaflets of the heart valve, and wherein the anchor and the valve are adapted for in vivo expansion and coupling to one another to form composite apparatus that endovascularly replaces the heart valve. The invention also includes a method for endovascularly replacing a patient's heart valve.Type: ApplicationFiled: December 23, 2003Publication date: June 23, 2005Applicant: Sadra MedicalInventors: Amr Salahieh, Dwight Morejohn, Jeff Krolik, Kenneth Michlitsch
-
Publication number: 20050137687Abstract: Apparatus for endovascularly replacing a patient's heart valve. In some embodiments the apparatus includes an expandable anchor with a lip region and a skirt region; and a replacement valve, wherein the lip region and skirt region are configured for percutaneous expansion to engage leaflets of the heart valve. The invention is also a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of endovascularly delivering apparatus including an anchor having lip and skirt regions, and a replacement valve coupled to the anchor, to a vicinity of the heart valve in a collapsed delivery configuration; and expanding the apparatus such that leaflets of the heart valve are captured between the lip and skirt regions of the anchor.Type: ApplicationFiled: December 23, 2003Publication date: June 23, 2005Applicant: Sadra MedicalInventors: Amr Salahieh, Brian Brandt, Dwight Morejohn, Ulrich Haug, Jean-Pierre Dueri, Hans Valencia, Robert Geshlider, Jeff Krolik