Abstract: An inactivated influenza virus preparation is described which comprises a haemagglutinin antigen stabilized in the absence of thiomersal, or at low levels of thiomersal, wherein the haemagglutinin is detectable by a SRD assay. The influenza virus preparation may comprise a micelle modifying excipient, for example ?-tocopherol or a derivative thereof in a sufficient amount to stabilize the haemagglutinin.
Type:
Grant
Filed:
May 29, 2002
Date of Patent:
January 8, 2008
Assignee:
Saechsisches Serumwerk Dresden Branch of SmithKline Beecham Pharma GmbH & Co KG